Results 71 to 80 of about 4,863,804 (250)

Computing the l,k-Clique Metric Dimension of Graphs via (Edge) Corona Products and Integer Linear Programming Model

Journal of Mathematics
Let G be a graph with n vertices and CG=X:X is an l-clique of G. A vertex v∈VG is said to resolve a pair of cliques X,Y in G if dGv,X≠dGv,Y where dG is the distance function of G. For a pair of cliques X,Y, the resolving neighbourhood of X and Y, denoted
Zeinab Shahmiri, Mostafa Tavakoli
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Edge Metric Dimension of Silicate Networks [PDF]

Metric dimension is an essential parameter in graph theory that aids in addressing issues pertaining to information retrieval, localization, network design, and chemistry through the identification of the least possible number of elements necessary to ...
Prabhu, S., Janany, T. Jenifer
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Load balance -aware dynamic cloud-edge-end collaborative offloading strategy.

PLoS ONE
Cloud-edge-end (CEE) computing is a hybrid computing paradigm that converges the principles of edge and cloud computing. In the design of CEE systems, a crucial challenge is to develop efficient offloading strategies to achieve the collaboration of edge ...
Yueqi Fan
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Edge participation coefficient unveiling the developmental dynamics of neonatal functional connectome

Communications Biology
Understanding how the brain’s functional connections develop during infancy is crucial for uncovering the complexities of early neural maturation. Traditional node-based analyses have advanced our knowledge, but may overlook the transient dynamics of ...
Tianyu Fang, Rong Wang, Weijin Liu, Yue Zhang, Yu Guo, Yichen Hu, Xin Zhao, Yuanyuan Chen, Qiuyun Fan, Dong Ming   +9 more
doaj   +1 more source

Using phylogenetic relationships to assess conservation priorities for birds in India

Global Ecology and Conservation
In the midst of the ongoing biodiversity crisis, setting conservation priorities has moved beyond conventional approaches. The need to incorporate phylogeny-based metrics that capture evolutionary rarity in conjunction with extinction risk has been ...
Archita Sharma, Naman Goyal, Dhyey Shah, V.V. Robin   +3 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source