Results 121 to 130 of about 238,609 (287)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Metric dimension of skeletal trees of unicyclic graphs [PDF]

open access: yes, 2019
Найменшу за потужнiстю множину M ∈ V скiнченного графа G = (V,E) таку, що для будьякої пари вершин u,v ∈ V iснує принаймнi одна вершина t ∈ M, для якої має мiсце нерiвнiсть dG(t,v) 6= dG(t,u), називають метричним базисом, а потужнiсть множини M ...
Дуденко, Маргарита
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Exploring the fault-tolerant metric dimension (FTMD) of the M-polynomial for zigzag edge coronoids fused with starphene [PDF]

open access: yes
Graph invariants are valuable tools for exploring the complex structures of molecular graphs, which have attracted significant interest from researchers across multiple disciplines.
Bayram, Mustafa   +5 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Fault-Tolerant Metric Dimension and Applications: Zero-Divisor Graph of Upper Triangular Matrices

open access: yesMathematics
Graph invariants play a crucial role in understanding the structural and combinatorial characteristics of graphs. The fault-tolerant metric dimension, as a significant graph invariant, finds applications in diverse areas such as robust network ...
Latif Abdelmalek Hanna   +2 more
doaj   +1 more source

On the edge metric dimension for the random graph

open access: yes, 2016
Let $G(V, E)$ be a connected simple undirected graph. In this paper we prove that the edge metric dimension (introduced by Kelenc, Tratnik and Yero) of the Erdős-Rényi random graph $G(n, p)$ is given by: $$\textrm{edim}(G(n, p)) = (1 + o(1))\frac{4\log(n)}{\log(1/q)},$$ where $q = 1 - 2p(1-p)^2(2-p)$.
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

An efficient way to represent the processors and their connections in omega networks

open access: yesAin Shams Engineering Journal
The understanding of the structure of a network can be enhanced efficiently with distance-reliant parameters. The metric dimension is one such parameter with numerous variations and a rich source of literature.
Savari Prabhu   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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