Results 31 to 40 of about 2,220,575 (234)

Disiplinlerarası araştırma ve eğitim [PDF]

open access: yes, 2007
Bu Bölümde disiplinlerarası yaklaşım ve küreselleşme ve getirdiği sorunlar arasındaki ilişki irdelenmekte; yönetim ve ekonomideki değişimlerin disiplinlerarası araştırma ve eğitim için yarattığı talep üzerinde durulmakta; üniversite paradigmasındaki ...
Ulusoy, Gunduz, Ulusoy, Gündüz
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Konaklama i̇şletmelerinin yeşil yıldız uygulamaları kapsamında çevreye duyarlılığının değerlendirilmesi [PDF]

open access: yes, 2018
Bu araştırmanın amacı, yeşil yıldız belgeli konaklama işletmelerinin çevreye duyarlılığını web siteleri üzerinden inceleyerek bu uygulamalardan hangilerine daha fazla vurgu yaptıklarını belirlemektir.
Ertaş, Mehmet   +3 more
core   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Examining of the Effects of Employees on Work Stress, Role Conflict and Job Insecurity on Organizational Culture [PDF]

open access: yes, 2019
Perceived work stress, It is stated that employees are psychologically disturbed and intensely threatening their health at their busy working tempo. Employees with a high degree of stress in the face of excessive workloads may experience burnout and ...
Adiguzel, Z. (Zafer)   +1 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

editörden

open access: yesArtuklu Akademi, 2017
edit
Ahmet Ağırakça
doaj  

Home - About - Disclaimer - Privacy