Results 101 to 110 of about 270,614 (275)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Computational Models of Symbolic Rhythm Similarity: Correlation with Human Judgments [PDF]

open access: yesAnalytical Approaches to World Music, 2011
A novel approach to describing rhythmic relationships in music is introduced by means of three experiments designed to test computational measures of symbolic rhythm similarity against human judgments.
Toussaint, Godfried T.   +2 more
doaj  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Discriminative application of string similarity methods to chemical and non-chemical names for biomedical abbreviation clustering

open access: yesBMC Genomics, 2012
Background Term clustering, by measuring the string similarities between terms, is known within the natural language processing community to be an effective method for improving the quality of texts and dictionaries.
Yamaguchi Atsuko   +4 more
doaj   +1 more source

Tree Edit Distance Learning via Adaptive Symbol Embeddings

open access: yes, 2018
Metric learning has the aim to improve classification accuracy by learning a distance measure which brings data points from the same class closer together and pushes data points from different classes further apart.
Gallicchio, Claudio   +3 more
core  

Fréchet Edit Distance

open access: yes
We define and investigate the Fréchet edit distance problem. Given two polygonal curves $π$ and $σ$ and a threshhold value $δ>0$, we seek the minimum number of edits to $σ$ such that the Fréchet distance between the edited $σ$ and $π$ is at most $δ$. For the edit operations we consider three cases, namely, deletion of vertices, insertion of vertices,
Fox, Emily   +3 more
openaire   +3 more sources

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Efficient algorithms for fast integration on large data sets from multiple sources

open access: yesBMC Medical Informatics and Decision Making, 2012
Background Recent large scale deployments of health information technology have created opportunities for the integration of patient medical records with disparate public health, human service, and educational databases to provide comprehensive ...
Mi Tian   +2 more
doaj   +1 more source

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