Results 101 to 110 of about 270,219 (278)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
BMC Bioinformatics, 2011 Background This paper is devoted to distance measures for leaf-labelled trees on free leafset. A leaf-labelled tree is a data structure which is a special type of a tree where only leaves (terminal) nodes are labelled.
Walczak Krzysztof, Koperwas Jakub
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
We define and investigate the Fréchet edit distance problem. Given two polygonal curves $π$ and $σ$ and a threshhold value $δ>0$, we seek the minimum number of edits to $σ$ such that the Fréchet distance between the edited $σ$ and $π$ is at most $δ$. For the edit operations we consider three cases, namely, deletion of vertices, insertion of vertices,
Fox, Emily +3 more
openaire +3 more sources
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Computational Models of Symbolic Rhythm Similarity: Correlation with Human Judgments [PDF]
Analytical Approaches to World Music, 2011 A novel approach to describing rhythmic relationships in music is introduced by means of three experiments designed to test computational measures of symbolic rhythm similarity against human judgments.
Toussaint, Godfried T. +2 more
doaj
On the Maximal Independent Sets of k-mers with the Edit Distance. [PDF]
ACM BCB, 2023 Ma L, Chen K, Shao M.
europepmc +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
BMC Genomics, 2012 Background Term clustering, by measuring the string similarities between terms, is known within the natural language processing community to be an effective method for improving the quality of texts and dictionaries.
Yamaguchi Atsuko +4 more
doaj +1 more source