Results 81 to 90 of about 34,882 (289)

On the Generative Power of ReLU Network for Generating Similar Strings

IEEE Access
Recently, generative networks are widely used in different applied fields including computational biology for data augmentation, DNA sequence generation, and drug discovery.
Mamoona Ghafoor, Tatsuya Akutsu
doaj   +1 more source

Edit-distance between visibly pushdown languages

, 2017
We study the edit-distance between two visibly pushdown languages. It is well-known that the edit-distance between two context-free languages is undecidable.
Yo-Sub Han, Han, YS, Ko, SK, Sang-Ki Ko
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

siEDM: An Efficient String Index and Search Algorithm for Edit Distance with Moves

Algorithms, 2016
Although several self-indexes for highly repetitive text collections exist, developing an index and search algorithm with editing operations remains a challenge.
Yoshimasa Takabatake, Kenta Nakashima, Tetsuji Kuboyama, Yasuo Tabei, Hiroshi Sakamoto   +4 more
doaj   +1 more source

A Quadratic Programming Approach to the Graph Edit Distance Problem

, 2007
. In this paper we propose a quadratic programming approach to computing the edit distance of graphs. Whereas the standard edit distance is defined with respect to a minimum-cost edit path between graphs, we introduce the notion of fuzzy edit paths ...
Michel Neuhaus, Horst Bunke, Neuhaus, Michel, Bunke, Horst   +3 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Classification of Pulse Waveforms Using Edit Distance with Real Penalty

EURASIP Journal on Advances in Signal Processing, 2010
Advances in sensor and signal processing techniques have provided effective tools for quantitative research in traditional Chinese pulse diagnosis (TCPD).
Dongyu Zhang, Wangmeng Zuo, David Zhang, Hongzhi Zhang, Naimin Li   +4 more
doaj   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Siamese neural network architecture for homoglyph attacks detection

ICT Express, 2020
Primarily an adversary uses homoglyph or spoofing attack approach to obfuscate domain name, file name or process names. This approach facilitates to create domain name, file name or process names which look visually homogeneous to legitimate domain name,
Vinayakumar R., Soman K.P.
doaj   +1 more source

Automatic Wrapper Adaptation by Tree Edit Distance Matching

, 2010
Information distributed through the Web keeps growing faster day by day,\ud and for this reason, several techniques for extracting Web data have been suggested\ud during last years.
Baumgartner, Robert, Ferrara, Emilio
core