Results 81 to 90 of about 1,791,230 (278)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

On the Generative Power of ReLU Network for Generating Similar Strings

open access: yesIEEE Access
Recently, generative networks are widely used in different applied fields including computational biology for data augmentation, DNA sequence generation, and drug discovery.
Mamoona Ghafoor, Tatsuya Akutsu
doaj   +1 more source

siEDM: An Efficient String Index and Search Algorithm for Edit Distance with Moves

open access: yesAlgorithms, 2016
Although several self-indexes for highly repetitive text collections exist, developing an index and search algorithm with editing operations remains a challenge.
Yoshimasa Takabatake   +4 more
doaj   +1 more source

Linear space string correction algorithm using the Damerau-Levenshtein distance

open access: yesBMC Bioinformatics, 2020
Background The Damerau-Levenshtein (DL) distance metric has been widely used in the biological science. It tries to identify the similar region of DNA,RNA and protein sequences by transforming one sequence to the another using the substitution, insertion,
Chunchun Zhao, Sartaj Sahni
doaj   +1 more source

PartSS: An Efficient Partition-based Filtering for Edit Distance Constraints [PDF]

open access: yes, 2011
This paper introduces PartSS, a new partition-based filtering for tasks performing string comparisons under edit distance constraints. PartSS offers improvements over the state-of-the-art method NGPP with the implementation of a new partitioning scheme ...
Sitbon, Laurianne   +2 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Classification of Pulse Waveforms Using Edit Distance with Real Penalty

open access: yesEURASIP Journal on Advances in Signal Processing, 2010
Advances in sensor and signal processing techniques have provided effective tools for quantitative research in traditional Chinese pulse diagnosis (TCPD).
Dongyu Zhang   +4 more
doaj   +2 more sources

Siamese neural network architecture for homoglyph attacks detection

open access: yesICT Express, 2020
Primarily an adversary uses homoglyph or spoofing attack approach to obfuscate domain name, file name or process names. This approach facilitates to create domain name, file name or process names which look visually homogeneous to legitimate domain name,
Vinayakumar R., Soman K.P.
doaj   +1 more source

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