Results 71 to 80 of about 1,895,967 (280)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Parameter-Free Extended Edit Distance [PDF]

open access: yes, 2014
The edit distance is the most famous distance to compute the similarity between two strings of characters. The main drawback of the edit distance is that it is based on local procedures which reflect only a local view of similarity.
Muhammad Marwan Muhammad Fuad   +1 more
core   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Lossless filter for multiple repeats with bounded edit distance

open access: yesAlgorithms for Molecular Biology, 2009
Background Identifying local similarity between two or more sequences, or identifying repeats occurring at least twice in a sequence, is an essential part in the analysis of biological sequences and of their phylogenetic relationship.
Pisanti Nadia   +4 more
doaj   +1 more source

Computing Edit Distance (Invited Talk)

open access: yes, 2021
The edit distance (or Levenshtein distance) between two strings x, y is the minimum number of character insertions, deletions, and substitutions needed to convert x into y.
Koucký, Michal
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

An edit distance between graph correspondences. [PDF]

open access: yes, 2017
The Hamming Distance has been largely used to calculate the dissimilarity of a pair of correspondences (also known as labellings or matchings) between two structures (i.e. sets of points, strings or graphs).
Serratosa, Francesc   +5 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

The Edit Distance for Reeb Graphs of Surfaces [PDF]

open access: yesDiscrete & Computational Geometry, 2016
An extended abstract of this work appeared in: E. Barcucci et al. (Eds.): DGCI 2014, LNCS 8668, pp.
DI FABIO, Barbara, LANDI, Claudia
openaire   +7 more sources

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Home - About - Disclaimer - Privacy