Results 61 to 70 of about 270,219 (278)

Edit distance with move operations

open access: yesJournal of Discrete Algorithms, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Shapira, Dana, Storer, James A.
openaire   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Efficient Algorithms for Computing the Inner Edit Distance of a Regular Language via Transducers

open access: yesAlgorithms, 2018
The concept of edit distance and its variants has applications in many areas such as computational linguistics, bioinformatics, and synchronization error detection in data communications.
Lila Kari   +3 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Evaluating Automatic Detection of Misspellings in German [PDF]

open access: yesLanguage Learning and Technology, 2008
his study investigates the performance of a spell checker designed for native writers on misspellings made by second language (L2) learners. It addresses two research questions: 1) What is the correction rate of a generic spell checker for L2 ...
Anne Rimrott, Trude Heift
doaj  

String correction using the Damerau-Levenshtein distance

open access: yesBMC Bioinformatics, 2019
Background In the string correction problem, we are to transform one string into another using a set of prescribed edit operations. In string correction using the Damerau-Levenshtein (DL) distance, the permissible edit operations are: substitution ...
Chunchun Zhao, Sartaj Sahni
doaj   +1 more source

Near-Linear Time Insertion-Deletion Codes and (1+$\varepsilon$)-Approximating Edit Distance via Indexing

open access: yes, 2019
We introduce fast-decodable indexing schemes for edit distance which can be used to speed up edit distance computations to near-linear time if one of the strings is indexed by an indexing string $I$.
Approximating   +6 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

A Binary Integer Programming model for computing DNA Sequence Alignment [PDF]

open access: yesAl-Rafidain Journal of Computer Sciences and Mathematics, 2010
DNA Sequence Alignment is an important problem in computational biology and is useful for comparing genomes and finding genes, for determining evolutionary linkage of different biological sequences.
Nawar Qubat
doaj   +1 more source

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