Results 61 to 70 of about 270,614 (275)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Edit distance with move operations
Journal of Discrete Algorithms, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Shapira, Dana, Storer, James A.
openaire +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
String correction using the Damerau-Levenshtein distance
BMC Bioinformatics, 2019 Background In the string correction problem, we are to transform one string into another using a set of prescribed edit operations. In string correction using the Damerau-Levenshtein (DL) distance, the permissible edit operations are: substitution ...
Chunchun Zhao, Sartaj Sahni
doaj +1 more source
, 2019 We introduce fast-decodable indexing schemes for edit distance which can be used to speed up edit distance computations to near-linear time if one of the strings is indexed by an indexing string $I$.
Approximating +6 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A Binary Integer Programming model for computing DNA Sequence Alignment [PDF]
Al-Rafidain Journal of Computer Sciences and Mathematics, 2010 DNA Sequence Alignment is an important problem in computational biology and is useful for comparing genomes and finding genes, for determining evolutionary linkage of different biological sequences.
Nawar Qubat
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Evaluating Automatic Detection of Misspellings in German [PDF]
Language Learning and Technology, 2008 his study investigates the performance of a spell checker designed for native writers on misspellings made by second language (L2) learners. It addresses two research questions: 1) What is the correction rate of a generic spell checker for L2 ...
Anne Rimrott, Trude Heift
doaj
JMIR Medical Informatics, 2021 BackgroundClinical terms mentioned in clinical text are often not in their standardized forms as listed in clinical terminologies because of linguistic and stylistic variations.
Kate, Rohit J
doaj +1 more source