Results 221 to 230 of about 4,250,670 (346)

vPE: Toward a new generation of error-free prime editing. [PDF]

Mol Ther Nucleic Acids
Jamil M, Zahra A, Maqbool R, Arshad MI, Khan SH.   +4 more
europepmc   +1 more source

Complete edition

História da Historiografia, 2011
openaire   +17 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Disrupting pegRNA intramolecular complementarity via PBS and spacer sequence alterations can enhance prime editing efficiency. [PDF]

Nucleic Acids Res
Biczók Z, Krausz SL, Simon DA, Tóth E, Varga É, Annus T, Huba F, Varga M, Bakos É, Fodor E, Welker E.   +10 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Management of gastric cancer peritoneal metastasis: International Gastric Cancer Association GCPM Working Group consensus statements. [PDF]

Br J Surg
Boshier PR, Chia DKA, Thrumurthy SG, Teh JL, Wobith M, Bencivenga M, Filippini F, Dumitra TC, Burch M, Kim HI, Kobitzsch B, Kodach LL, Quik JSE, Long VD, de Neijs MJ, van der Sluis PC, Leon-Takahashi AM, Woo Y, Chevallay M, Framarini M, Morgagni P, Frejlich E, Grabsch HI, Markar SR, Marrelli D, Park DJ, Sundar R, Xu Z, Linn KK, Yang HK, Kitayama J, Zhu Z, Rha SY, Wijnhoven B, Yamashita H, Yong WP, de la Fouchardière C, Nilsson M, Ishigami H, Van Sandick JW, Lordick F, Badgwell BD, So JBY.   +42 more
europepmc   +1 more source