Results 91 to 100 of about 4,857,848 (301)

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source

Atrophic Skeletal Muscle‐Derived Extracellular Vesicles Transfer miR‐125a‐5p to Inhibit Bone Formation in Osteoporosis during Aging

Advanced Science, EarlyView.
A muscle‐bone endocrine pathway in aging is revealed in which extracellular vesicles released from atrophic skeletal muscle (Aged‐SKM‐EVs) inhibit bone formation. These EVs deliver miR‐125a‐5p to osteoblasts, thereby suppressing the SIRT7‐Sp7 signaling axis and osteogenic differentiation.
Xiaoyan Shao, Pan Zhang, Zhidan Fan, Jiaquan Lin, Xiang Chen, Na Liu, Wang Gong, Yi He, Yining Zhou, Tianshu Shi, Yong Shi, Yuze Ma, Wentian Gao, Haosheng Wang, Depeng Fang, Chengzhi Wang, Wenshu Wu, Wenjin Yan, Jianghui Qin, Dongyang Chen, Haiguo Yu, Qing Jiang, Baosheng Guo   +22 more
wiley   +1 more source

Symposium Presenters [PDF]

, 2017
Listing of symposium presenters and their institutional ...
Editorial Board
core   +1 more source

Coronavirus infection (COVID-19) in Anales de Pediatría

Anales de Pediatría (English Edition), 2020
Corsino Rey Galán, Laia Alsina Manrique de Lara, Montserrat Antón Gamero, Alfredo Cano Garcinuño, Gonzalo Solís Sánchez   +4 more
doaj   +1 more source

Realidad de la Revista Chilena de Radiología 2010-2014

Revista Chilena de Radiología
El presente artículo tiene como finalidad la revisión editorial de la Revista Chilena de Radiología en el período 2010 al 2014. Durante el período se publicaron 162 artículos, de los cuales 138 fueron artículos originales, artículos de revisión o ...
Marcelo Gálvez M, Patricio Gana G, Paulina Gana P, Sonia Rivas H   +3 more
doaj   +1 more source

Editorial [PDF]

Mycoses, 2004
Müller, J, Knoke, M
openaire   +2 more sources

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Gaceta Sanitaria en 2015

Gaceta Sanitaria, 2016
Carme Borrell, Mª Felicitas Domínguez-Berjón, Carlos Álvarez-Dardet, Clara Bermúdez-Tamayo, Pere Godoy, María José López, Miguel Angel Negrín, Glòria Pérez, Napoleón Pérez-Farinós, Alberto Ruano, Carmen Vives Cases, Rosana Peiró, Iñaki Galán   +12 more
doaj   +1 more source

In Memoriam of Andrew Webster

New Genetics and Society, 2022
Richard Tutton, Adam Hedgecoe, Gareth Thomas, Ros Williams, Clancy Pegg   +4 more
doaj   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source