Results 91 to 100 of about 1,278,440 (295)

Unrelated Future Costs and Unrelated Future Benefits:Reflections on NICE Guide to the Methods of Technology Appraisal [PDF]

open access: yes, 2016
In this editorial, we consider the vexing issue of 'unrelated future costs' (for example, the costs of caring for people with dementia or kidney failure after preventing their deaths from a heart attack).
Adler, Amanda I   +9 more
core   +3 more sources

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

open access: yesAdvanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia   +6 more
wiley   +1 more source

Practice editorial [PDF]

open access: yesPRACTICE, 2021
openaire   +1 more source

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

open access: yesAdvanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang   +17 more
wiley   +1 more source

Collectivity and Criticism: (Fragments of) Conversations on Post-dance [PDF]

open access: yes, 2018
Post-dance first unfolded as a conference in MDT in Stockholm, 14-16 October, 2015, created by Danjel Andersson, Andre Lepecki and Gabriel Smeds, and was followed by a multi-authored publication co-edited by Andersson, Mette Edvardsen and Mårten ...
LO GATTO, Sergio
core  

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu   +7 more
wiley   +1 more source

Magnetic and Crystal Symmetry Control on Spin Hall Conductivity in Altermagnets

open access: yesAdvanced Science, EarlyView.
Crystal structures and schematic illustrations of the spin Hall effect (SHE) in altermagnets. High‐symmetry RuO2 exhibits conventional SHE, while tilted RuO2 shows trivial unconventional SHE (USHE) caused by structural tilting. CrSb and MnTe, with reduced magnetic symmetry, display intrinsic USHE arising from symmetry‐driven spin–momentum locking ...
Dameul Jeong   +2 more
wiley   +1 more source

The ‘rise and fall’ of a genre: the generic and rhetorical renditions of a Runyankore-Rukiga editorial

open access: yesStellenbosch Papers in Linguistics Plus, 2019
This article explores the discursive practice of editorial writing in Runyankore-Rukiga print media. It also explicates the generic structure of Runyankore-Rukiga editorial text and the rhetorical devices that the editorial writers have invoked to ...
Mugumya, Levis
doaj   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

open access: yesAdvanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini   +24 more
wiley   +1 more source

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