Results 71 to 80 of about 1,424,891 (239)

Fact sheets for editors in Organic Eprints [PDF]

open access: yes, 2011
There are many editors of different kinds in Organic Eprints, such as conference editors, institutional editors, project editors and, in particular, 33 national editors.
Rasmussen, Ilse A.
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

IJIMAI Editor’s Note - Vol. 2 Issue 1

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence, 2013
This special issue “Artificial Intelligence and Social Application” includes extended versions of selected papers from Artificial Intelligence and Education area of the 13th edition of the Ibero-American Conference on Artificial Intelligence, held in ...
Elisa Boff, Juan Pavón Mestras
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Editor’s Note [PDF]

open access: yesJournal of the Pediatric Infectious Diseases Society, 2012
D. Wayne Osgood   +2 more
openaire   +5 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Editorial: A New Chapter for IJIMAI.

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence
The history of IJIMAI is a story of commitment, inclusion, and accessibility within the academic world. Since its founding, the journal has aimed to provide an open, free, and high-quality space for researchers and professionals in the fields of ...
Rubén González Crespo
doaj   +1 more source

Ethical Bedrock Under a Changing Negotiation Landscape [PDF]

open access: yes, 2017
Editors\u27 Note: Your dilemmas as a negotiator fall into two basic sets, “what’s possible?” and “what\u27s right?” The first is treated by many chapters in this book.
Gibson, Kevin
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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