Results 1 to 10 of about 4,486 (172)

EDMD-Causing Emerin Mutant Myogenic Progenitors Exhibit Impaired Differentiation Using Similar Mechanisms [PDF]

Cells, 2020
Mutations in the gene encoding emerin (EMD) cause Emery–Dreifuss muscular dystrophy (EDMD1), an inherited disorder characterized by progressive skeletal muscle wasting, irregular heart rhythms and contractures of major tendons.
James M Holaska
exaly   +5 more sources

Study of the Hypergeometric Equation via Data Driven Koopman-EDMD Theory

Axioms, 2023
We consider a data-driven method, which combines Koopman operator theory with Extended Dynamic Mode Decomposition. We apply this method to the hypergeometric equation which is the Fuchsian equation with three regular singular points.
Costas Poulios, Elias Camouzis, Nick Poulios   +2 more
exaly   +5 more sources

LINC complex alterations in DMD and EDMD/CMT fibroblasts [PDF]

European Journal of Cell Biology, 2012
Emery-Dreifuss muscular dystrophy (EDMD) is a late onset-disease characterized by skeletal muscle wasting and heart defects with associated risk of sudden death. The autosomal dominant form of the disease is caused by mutations in the LMNA gene encoding LaminA and C, the X-linked form results from mutations in the gene encoding the inner nuclear ...
James Robert Carthew, Peter Meinke, Sabu Abraham   +2 more
exaly   +3 more sources

ACD-EDMD: Analytical Construction for Dictionaries of Lifting Functions in Koopman Operator-Based Nonlinear Robotic Systems [PDF]

IEEE Robotics and Automation Letters, 2022
Accepted to IEEE Robotics and Automation Letters (RA-L), November ...
Lu Shi, Konstantinos Karydis
exaly   +3 more sources

EDMD for expanding circle maps and their complex perturbations

Applied and Computational Harmonic Analysis
18 pages, 4 ...
Oscar Bandtlow
exaly   +4 more sources

Recursive Forward-Backward EDMD: Guaranteed Algebraic Search for Koopman Invariant Subspaces

IEEE Access
The implementation of the Koopman operator on digital computers often relies on the approximation of its action on finite-dimensional function spaces. This approximation is generally done by orthogonally projecting on the subspace.
Masih Haseli, Jorge Cortes
doaj   +2 more sources

Echocardiographic Features of Cardiomyopathy in Emery-Dreifuss Muscular Dystrophy

Cardiology Research and Practice, 2021
Background. Emery-Dreifuss muscular dystrophy (EDMD) is a very rare type of muscular dystrophy characterized by musculoskeletal abnormalities accompanied by cardiac defects.
Michał Marchel, Agnieszka Madej-Pilarczyk, Agata Tymińska, Roman Steckiewicz, Janusz Kochanowski, Julia Wysińska, Ewa Ostrowska, Paweł Balsam, Marcin Grabowski, Grzegorz Opolski   +9 more
doaj   +1 more source

Investigating the electrical discharge micro drilling for porous architecture in magnesium alloy

International Journal of Lightweight Materials and Manufacture, 2022
Three-dimensional porous architectures (also called scaffolds) of magnesium (Mg) alloys are now highly prevalent for tissue engineering to enable favourable physical and biological environmental support in bone healing.
Lalit Kumar, Kamal Kumar
doaj   +1 more source

Surgical Treatment for Severe Cervical Hyperlordosis and Thoracolumar Kyphoscoliosis with Emery–Dreifuss Muscular Dystrophy: A Case Report and Literature Review

Orthopaedic Surgery, 2022
Background Emery–Dreifuss muscular dystrophy (EDMD) is an uncommon, gradually progressive X‐linked myopathy, and it could result in rigid spinal deformity.
Ziyang Tang, Zongshan Hu, Xiaodong Qin, Zezhang Zhu, Zhen Liu   +4 more
doaj   +1 more source

A multistage sequencing strategy pinpoints novel candidate alleles for Emery-Dreifuss muscular dystrophy and supports gene misregulation as its pathomechanism

EBioMedicine, 2020
Background: As genome-wide approaches prove difficult with genetically heterogeneous orphan diseases, we developed a new approach to identify candidate genes.
Peter Meinke, Alastair R.W. Kerr, Rafal Czapiewski, Jose I. de las Heras, Charles R. Dixon, Elizabeth Harris, Heike Kölbel, Francesco Muntoni, Ulrike Schara, Volker Straub, Benedikt Schoser, Manfred Wehnert, Eric C. Schirmer   +12 more
doaj   +1 more source