Results 41 to 50 of about 16,411 (192)

Impact of Edoxaban on Thrombin-Dependent Platelet Aggregation

Clinical and Applied Thrombosis/Hemostasis, 2020
Edoxaban, a direct factor Xa inhibitor (FXa), is the fourth direct oral anticoagulant (DOAC) approved for clinical use. As the main adverse event is bleeding, it is relevant whether edoxaban has additional effects on platelet function. We aimed to assess
Juraj Sokol MD, PhD, Frantisek Nehaj MD, Jela Ivankova RNDr, Michal Mokan MD, PhD, Lenka Lisa MD, PhD, Jana Zolkova RNDr, Lubica Vadelova RNDr, Marian Mokan Prof, MD, DSc, FRCP Edin, Jan Stasko Prof, MD, PhD   +8 more
doaj   +1 more source

Electronic monitoring of adherence to once‐daily and twice‐daily direct oral anticoagulants in patients with atrial fibrillation: Baseline data from the SMAAP‐AF trial

Journal of Arrhythmia, 2021
Background Nonadherence diminishes the efficacy of direct oral anticoagulants (DOACs) in patients with nonvalvular atrial fibrillation (NVAF). This report presents the baseline survey results regarding medication adherence among NVAF patients who were ...
Tsuyoshi Shiga, Toshimi Kimura, Noritoshi Fukushima, Yuji Yoshiyama, Kazunori Iwade, Fumiaki Mori, Yoichi Ajiro, Shoji Haruta, Yuichiro Yamada, Emi Sawada, Nobuhisa Hagiwara, the SMAAP‐AF investigators   +11 more
doaj   +1 more source

A Renal Function Based Trade-Off Analysis of Non-vitamin K Antagonist Oral Anticoagulants in Nonvalvular Atrial Fibrillation

Frontiers in Physiology, 2018
Background: Non-vitamin K antagonist oral anticoagulants (NOACs) depend on some degree of renal excretion, and no head-to-head comparisons based on renal function is available. This study mainly investigated the trade-off property of NOACs in nonvalvular
Ling-Yun Zhou, Shuo-Fei Yang, Zhen Zhang, Chi Zhang, Long Shen, Zhi-Chun Gu, Xiao-Cong Zuo   +6 more
doaj   +1 more source

State of play and future direction with NOACs: An expert consensus. [PDF]

, 2018
Atrial fibrillation (AF) and venous thromboembolism (VTE) are cardiovascular conditions significant in contemporary practice. In both, the use of anticoagulation with vitamin K antagonists (VKAs) has been traditionally used to prevent adverse events ...
A.J. Camm, A.T. Cohen, Ageno, Agnelli, Alings, Ansell, Ansell, Apostolakis, Avgil-Tsadok, Beyer-Westendorf, Beyer-Westendorf, Beyer-Westendorf, Bohula, Bouillon, Brunner-Ziegler, Caldeira, Caldeira, Camm, Cannon, Cohen, Cohen, Coleman, Connolly, Connolly, Connolly, Cronin-Fenton, De Caterina, De Caterina, De Caterina, De Caterina, Diener, Diener, Diener, Douketis, Easton, Eikelboom, Ensor, F. Verheugt, Fang, Fauchier, Forslund, Fox, Friberg, Friberg, Furugohri, G. Agnelli, G.Y. Lip, Gage, Gibson, Giugliano, Glund, Granger, Gross, Guo, H. Heidbuchel, Hankey, Heidbuchel, Heidbuchel, Heit, Heit, Hijazi, Hohnloser, Husted, Investigators, J.L. Zamorano, Kearon, Keeling, Khorana, Kirchhof, Kooiman, Kooistra, Larsen, Levy, Lip, Lip, Lip, Lip, Lip, Lublóy, Martinez, Masjuan, Mendell, Mendell, Miyasaka, Moore, Morgan, Mungall, Murphy, Márquez-Contreras, Nielsen, Oldgren, Paciaroni, Paciaroni, Patel, Perzborn, Peterson, Pinto, Pollack, Pollack, Price, Prins, Proietti, Proietti, R. De Caterina, Raskob, Renda, Roffi, Roldán, Ruff, Ruff, Sandén, Sardar, Sardar, Sarich, Schulman, Schulman, Senoo, Senoo, Shekelle, Sjögren, Song, Stacy, Stampfuss, Stangier, Steinberg, Tafur, The EINSTEIN investigators, The EINSTEIN–PE Investigators, van der Hulle, van Walraven, Verhamme, Vrijens, Watanabe, Weitz, Wolf, Zamorano   +135 more
core   +5 more sources

NOACs versus warfarin for stroke prevention in patients with AF : a systematic review and meta-analysis [PDF]

, 2016
Acknowledgments Revman software was used for meta-analysis, a free download from the Cochrane Collaboration. GRADE pro software was used to formulate the GRADE summary of findings table, a free download from the GRADE working group.Peer reviewedPublisher
Eisinga, Anne, Hicks, Tim, Stewart, Fiona   +2 more
core   +1 more source

Association between SLCO1B1 genetic polymorphisms and bleeding risk in patients treated with edoxaban

Scientific Reports, 2023
Since SLCO1B1 encodes the uptake transporter OATP1B1, which can influence the pharmacokinetic and pharmacodynamic profiles of edoxaban, polymorphisms in SLCO1B1 may affect the edoxaban response.
Ji Min Han, Eun Jeong Jang, Jeong Yee, Tae-Jin Song, Dong-Hyeok Kim, Junbeom Park, Hye Sun Gwak   +6 more
doaj   +1 more source

Successful treatment of deep vein thrombosis caused by iliac vein compression syndrome with a single-dose direct oral anti-coagulant [PDF]

, 2017
BACKGROUND: Although vein stenting is popular for treatment for venous thromboembolism due to mechanical compression, some cases are forced to avoid inserting align agents because of immunodeficiency.
Daisuke Sueta, Eiichiro Yamamoto, Hisanori Kanazawa, Kenichi Tsujita, Koichi Kaikita, Naoya Nakashima, Seiji Hokimoto, Seiji Takashio, Shinsuke Hanatani, Sunao Kojima, Yasuhiro Izumiya, Yusuke Kanemaru   +11 more
core   +1 more source

Pre‐Existing and New‐Onset Atrial Fibrillation in Patients Undergoing Transcatheter Aortic Valve Implantation

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Atrial fibrillation (AF) is a frequent comorbidity in patients with severe aortic valve stenosis undergoing transcatheter aortic valve implantation (TAVI). In addition, new‐onset AF can occur after TAVI. However, data on how AF affects outcomes in patients undergoing TAVI remain conflicting.
Kimberley I. Hemelrijk, Astrid C. van Nieuwkerk, Philomene J. Vojacek, Livia Gheorge, Didier Tchétché, Fabio S. de Brito Jr., Marco Barbanti, Ran Kornowski, Azeem Latib, Augusto D'Onofrio, Flavio Ribichini, Geoffrey Yanes Bowden, Nicolas Dumonteil, Rogerio Sarmento Leite, Samantha Sartori, Paola D'Errigo, Giuseppe Tarantini, Stefano Andreaggi, Katia Orvin, Matteo Pagnesi, Lluis Asmarats, George Dangas, Roxana Mehran, Ronak Delewi   +23 more
wiley   +1 more source

Effectiveness of edoxaban in portal vein thrombosis associated with liver cirrhosis

Scientific Reports
Portal vein thrombosis (PVT) worsens the long-term prognosis of patients with cirrhosis; however, the optimal treatment remains to be determined. Reports on the efficacy of direct oral anticoagulants are increasing, and further evidence is needed ...
Tomoko Tadokoro, Joji Tani, Takushi Manabe, Kei Takuma, Mai Nakahara, Kyoko Oura, Shima Mimura, Koji Fujita, Takako Nomura, Asahiro Morishita, Hideki Kobara, Takashi Himoto, Masafumi Ono, Tsutomu Masaki   +13 more
doaj   +1 more source

The role of edoxaban in preventing thromboembolic complications in patients with atrial fibrillation

Атеротромбоз, 2020
Edoxaban is a selective direct factor Xa inhibitor. Edoxaban in a dose of 60 mg per day is an effective and safe option in the prevention of thromboembolic complications in patients with nonvalvular atrial fibrillation, including in combination therapy ...
O. O. Shakhmatova
doaj   +1 more source