Results 61 to 70 of about 12,163 (174)

Predictive Factors and Clinical Events Associated with Edoxaban Interruption and Heparin Bridging Strategy: EMIT-AF/VTE

Clinical and Applied Thrombosis/Hemostasis, 2023
Patients treated with edoxaban may require diagnostic and therapeutic procedures that involve edoxaban interruption. Although heparin bridging strategies are not recommended, heparin is frequently used in clinical practice.
Amparo Santamaria MD, PhD, Cathy Chen MD, Paolo Colonna MD, FESC, Christian von Heymann MD, PhD, Manish Saxena MBBS, MSc, FBHS, Thomas Vanassche MD, PhD, James Jin PhD, Martin Unverdorben MD, PhD   +7 more
doaj   +1 more source

Expert Consensus Statement: Committee on Implantable Devices and Committee on Social Issues, Japanese Heart Rhythm Society (JHRS) Statement on Remote Monitoring of Cardiac Implantable Electronic Devices

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
This statement of the Japanese Heart Rhythm Society (JHRS) provides comprehensive guidance for medical professionals and device manufacturers involved in RM. ABSTRACT Remote monitoring (RM) has been established as a standard tool for the management of patients with cardiac implantable electronic devices (CIEDs), offering advantages such as early event ...
Eiichi Watanabe, Nobuhiro Nishii, Akiko Maeda, Yoshiro Sakai, Katsuhito Fujiu, Makoto Suzuki, Ritsushi Kato, Haruhiko Abe, Takashi Noda, Hiroshi Tada, Masahiko Takagi   +10 more
wiley   +1 more source

Risk of Severe Hypoglycemia Associated With Concomitant Use of Sulfonylureas and Amiodarone

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9336-9345, October 2026.
ABSTRACT Aims To evaluate whether initiation of amiodarone while receiving sulfonylurea is associated with an increased risk of severe hypoglycemia compared with the initiation of other antiarrhythmic agents (flecainide, sotalol, or propafenone) while receiving sulfonylurea. Materials and Methods We conducted a population‐based cohort study using South
Sungho Bea, Hyesung Lee, Young Min Cho, You‐Jung Choi, Ju‐Young Shin, Katsiaryna Bykov   +5 more
wiley   +1 more source

Distribution of anti‐factor Xa activity in patients with nonvalvular atrial fibrillation receiving 15 mg dose of edoxaban

Journal of Arrhythmia
Background The distribution of anti‐factor Xa activity (AXA) in patients with nonvalvular atrial fibrillation (NVAF) taking edoxaban 15 mg has not been fully elucidated. Methods and Results The trough and peak AXA were measured in 19 NVAF patients taking
Shotaro Hiramatsu, Hiroyuki Osanai, Yuichiro Sakai, Yoshiki Sogo, Yuki Tanaka, Hikari Matsumoto, Shun Miyamoto, Kensuke Tagahara, Kenji Arai, Takashi Watanabe, Yusuke Sakamoto, Teruhiro Sakaguchi, Shioh Oguchi, Takahiro Kanbara, Yoshihito Nakashima, Hiroshi Asano, Masayoshi Ajioka   +16 more
doaj   +1 more source

The Impact of a Visualized Steerable Sheath on Radiofrequency Catheter Ablation for First‐Time Atrial Fibrillation Ablation: A Prospective, Randomized, Single‐Blind Study

Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 924-934, September 1, 2026.
ABSTRACT Background A 3D electroanatomical mapping (3D‐EAM) visualized steerable sheath was designed to improve catheter placement and reduce radiation exposure during ablation, an established treatment for atrial fibrillation (AF). However, prospective randomized data comparing the procedural and clinical outcomes of visualized and non‐visualized ...
Chun‐Kai Chen, Chih‐Chieh Yu, Min‐Tsun Liao, Hui‐Chun Huang, Yen‐Bin Liu   +4 more
wiley   +1 more source

Population pharmacokinetics and pharmacogenomics of edoxaban in Japanese adults with atrial fibrillation

Journal of Pharmaceutical Health Care and Sciences
Background Edoxaban is used as an anti-coagulant to prevent cardioembolic infarction, deep vein thrombosis, and pulmonary embolism. Edoxaban pharmacokinetics have been reported to be affected by several factors such as renal function, age, body weight ...
Satoshi Ueshima, Daiki Hira, Sayana Matsuda, Rio Michihata, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Moritake Iguchi, Masaharu Akao, Takanori Aizawa, Asami Kashiwa, Satoshi Shizuta, Takeru Makiyama, Yoshihisa Nakagawa, Minoru Horie, Tomohiro Terada, Toshiya Katsura   +16 more
doaj   +1 more source

Net Renal Drug Secretion Critically Requires Significant Contribution of Basal Uptake Transporters: Perspective From Mechanistic Kidney Model Simulation and Integration of Clinical and In Vitro Data

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACT Renal clearance (CLr) is the net outcome of glomerular filtration, secretion, and reabsorption, which makes the quantitative requirements for net renal secretion difficult to infer from simple clearance models. Using a mechanistic kidney model (MechKiM), we simulated blood‐referenced CLr (CLr,b) for 30,000 virtual drugs (neutral, monoanionic ...
Toshiaki Tsuchitani, Masatoshi Tomi, Yuichi Sugiyama   +2 more
wiley   +1 more source

Bilateral Bloody Pleural Effusions With Discordant Cellular Patterns: A Case of Concurrent Parapneumonic Effusion and Dressler Syndrome

Respirology Case Reports, Volume 14, Issue 9, September 2026.
This case demonstrates a rare concurrent presentation of parapneumonic effusion and Dressler syndrome, which presented as bilateral bloody pleural effusions with discordant cellular profiles. The bloody nature was possibly exacerbated by the concomitant use of a direct oral anticoagulant and aspirin.
Yoshitsugu Narumi, Susumu Hoshino, Midori Yamakawa, Yoshiko Amano   +3 more
wiley   +1 more source

Bleeding risk and mortality of edoxaban: a pooled meta-analysis of randomized controlled trials. [PDF]

PLoS ONE, 2014
Edoxaban, a factor Xa inhibitor, is a new oral anticoagulant that has been developed as an alternative to vitamin K antagonists. However, its safety remains unexplored.Medline, Embase and Web of Science were searched to March 8, 2014 for prospective ...
Shuang Li, Baoxin Liu, Dachun Xu, Yawei Xu   +3 more
doaj   +1 more source

Digital Health Interventions to Improve Medication Adherence Among Older Adults: A Systematic Review

Australasian Journal on Ageing, Volume 45, Issue 3, September 2026.
ABSTRACT Objective To review evidence on the type, characteristics and effect of digital health interventions (DHIs) on medication adherence among older people. Methods Articles were searched from inception to May 2025 in PubMed, Embase, CINAHL, Scopus and Web of Science.
Kaleab Taye Haile, Wejdan Shahin, Eyob Alemayehu Gebreyohannes, Abdella Birhan Yabeyu, Amina Hareem, Mulugeta Hayelom Kalayou, Xun Yi, Kate Wang   +7 more
wiley   +1 more source