Results 71 to 80 of about 16,411 (192)

More, More, More: Reducing Thrombosis in Acute Coronary Syndromes Beyond Dual Antiplatelet Therapy-Current Data and Future Directions. [PDF]

, 2018
© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.Common to the pathogenesis of acute coronary syndromes (ACS) is the formation of arterial thrombus, which results from platelet activation and triggering of the ...
Farag M, Hirsh J, Ibanez B, Mega JL, Park KW, Suh JW, Valgimigli M   +6 more
core   +3 more sources

Intravenous Tolvaptan Sodium Phosphate Can Fail to Improve Fluid Overload Due to Heart Failure in Patients With Chronic Kidney Disease: A Case Report

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Tolvaptan is widely used as an adjunct oral diuretic to loop and thiazide diuretics for the management of fluid overload in patients with congestive heart failure. Recently, tolvaptan sodium phosphate (TSP), a water‐soluble prodrug of tolvaptan, was developed for intravenous administration and has demonstrated efficacy and safety in clinical ...
Takaya Uno, Ichiro Nakakura, Akari Ikeda, Atsuki Hosoda, Yutaro Mukai, Kaori Yamanishi, Naohiro Ohara, Kaori Imanishi, Yoshiko Une, Satoshi Yokoyama, Kouichi Hosomi   +10 more
wiley   +1 more source

Distribution of anti‐factor Xa activity in patients with nonvalvular atrial fibrillation receiving 15 mg dose of edoxaban

Journal of Arrhythmia
Background The distribution of anti‐factor Xa activity (AXA) in patients with nonvalvular atrial fibrillation (NVAF) taking edoxaban 15 mg has not been fully elucidated. Methods and Results The trough and peak AXA were measured in 19 NVAF patients taking
Shotaro Hiramatsu, Hiroyuki Osanai, Yuichiro Sakai, Yoshiki Sogo, Yuki Tanaka, Hikari Matsumoto, Shun Miyamoto, Kensuke Tagahara, Kenji Arai, Takashi Watanabe, Yusuke Sakamoto, Teruhiro Sakaguchi, Shioh Oguchi, Takahiro Kanbara, Yoshihito Nakashima, Hiroshi Asano, Masayoshi Ajioka   +16 more
doaj   +1 more source

Cost-Utility Analysis of Venous Thromboembolism Prophylaxis Strategies for People Undergoing Elective Total Hip and Total Knee Replacement Surgeries in the English National Health Service [PDF]

, 2018
Background: Major orthopedic surgery, such as elective total hip replacement (eTHR) and elective total knee replacement (eTKR), are associated with a higher risk of venous thromboembolism (VTE) than other surgical procedures.
Anderson, Annemans, Arya, Barco, Bischof, Bjorvatn, Botteman, Braidy, Brockbank, Capri, Caprini, Cohoon, Curtis, Dahl, Dahl, Davies, Diamantopoulos, Dranitsaris, Dranitsaris, Ende-Verhaar, Gomez-Outes, Gordois, Gould, Haentjens, Hamidi, Hauck, Heit, Husereau, Jameson, Jameson, Kahn, Kapoor, Lundkvist, McCullagh, McCullagh, McDonald, Migliaccio-Walle, Postma, Quinlan, Reeves, Revankar, Riemsma, Roberts, Ryttberg, Sterne, Stevenson, Wade, Wang, Warwick, White, Wille-Jørgensen, Wolowacz, Wolowacz, Zindel   +53 more
core   +4 more sources

Essential Renal Bleeding Presenting as Persistent Unilateral Hematuria Successfully Treated With Factor XIII Replacement Therapy: A Case Report

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Essential renal bleeding is rare and lacks standardized treatment; organ‐preserving options are critical in older patients with impaired renal function. Case Presentation A woman in her early 80s with atrial fibrillation treated with edoxaban, chronic heart failure, and advanced chronic kidney disease presented with gross ...
Moe Toyoshima, Shigekatsu Maekawa, Arisa Machida, Kie Sekiguchi, Daiki Ikarashi, Renpei Kato, Mitsugu Kanehira, Jun Sugimura, Wataru Obara   +8 more
wiley   +1 more source

The Edoxaban Hokusai VTE PEDIATRICS Study: An open‐label, multicenter, randomized study of edoxaban for pediatric venous thromboembolic disease

Research and Practice in Thrombosis and Haemostasis, 2020
Background Little evidence is available for treatment of pediatric venous thromboembolism (VTE). Large randomized controlled trials are challenging in children.
Cornelia Heleen vanOmmen, Manuela Albisetti, Anthony K. Chan, Jeremie Estepp, Julie Jaffray, Gili Kenet, Guy Young, Jay Dave, Michael A. Grosso, Anil Duggal   +9 more
doaj   +1 more source

Research and Scholarly Methods: Scoping Reviews

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 5, May 2026.
ABSTRACT Scoping reviews are similar to systematic reviews in that they are designed to be transparent and reproducible processes to answer a question while reducing bias. The key difference between scoping reviews and the better‐known systematic review method is the scope of the question being answered.
Jason B. Reed, Amina Ammar, Christopher Giuliano   +2 more
wiley   +1 more source

Population pharmacokinetics and pharmacogenomics of edoxaban in Japanese adults with atrial fibrillation

Journal of Pharmaceutical Health Care and Sciences
Background Edoxaban is used as an anti-coagulant to prevent cardioembolic infarction, deep vein thrombosis, and pulmonary embolism. Edoxaban pharmacokinetics have been reported to be affected by several factors such as renal function, age, body weight ...
Satoshi Ueshima, Daiki Hira, Sayana Matsuda, Rio Michihata, Yohei Tabuchi, Tomoya Ozawa, Hideki Itoh, Moritake Iguchi, Masaharu Akao, Takanori Aizawa, Asami Kashiwa, Satoshi Shizuta, Takeru Makiyama, Yoshihisa Nakagawa, Minoru Horie, Tomohiro Terada, Toshiya Katsura   +16 more
doaj   +1 more source

A mixed methodology, non-interventional study to evaluate the use of direct oral anticoagulants in UK clinical practice for patients with a first stroke associated with non-valvular atrial fibrillation: study protocol. [PDF]

, 2019
BACKGROUND: Treatment with anticoagulants, including direct oral anticoagulants (DOACs), should be considered for patients diagnosed with atrial fibrillation (AF) deemed at risk of ischaemic stroke.
Bhat, Y, Dixit, A, Mistri, A, Patel, B, Quoraishi, SH, Uprichard, J   +5 more
core   +1 more source

A Case of Annular Pustular Psoriasis Possibly Triggered by Cabozantinib and Edoxaban During Nivolumab Therapy

The Journal of Dermatology, EarlyView.
Mana Nagatake, Hiroto Horikawa, Risa Kakuta, Takeya Adachi, Keishiro Fukumoto, Masayuki Amagai, Yoshihiro Ito   +6 more
wiley   +1 more source