Results 71 to 80 of about 12,163 (174)

Managing patients taking edoxaban in dentistry [PDF]

, 2017
Anticoagulation therapy is used in several conditions to prevent or treat thromboembolism. A new group of oral anticoagulants with clear advantages over classic dicoumarin oral anticoagulants (warfarin and acenocoumarol) has been developed in recent ...
Sanchez, Jorge, Curto Aguilera, Adrián, Curto, Daniel   +2 more
core  

Withholding Oral Anticoagulation at Discharge and Post‐Discharge Stroke and Bleeding Vulnerability in a Predominantly Older Cohort Hospitalized With Acute Heart Failure and Atrial Fibrillation

Geriatrics &Gerontology International, Volume 26, Issue 9, September 2026.
Among 560 predominantly older patients discharged after acute heart failure with atrial fibrillation, withholding oral anticoagulation was associated with higher ischemic stroke and did not indicate lower bleeding risk. Bleeding risk was significantly higher among patients aged 80 years or older.
Jumpei Yamamoto, Keijiro Nakamura, Hiromasa Hayama, Yoshinari Enomoto, Masaya Yamamoto, Hidehiko Hara, Hisao Hara, Yukio Hiroi   +7 more
wiley   +1 more source

Anticoagulant effects of edoxaban in cancer and noncancer patients with venous thromboembolism

Thrombosis Journal
Background Edoxaban, a direct oral anticoagulant (DOAC), is a first-line treatment for venous thromboembolism (VTE) and the suppression of VTE recurrence.
Masashi Yoshida, Kentaro Ejiri, Naoaki Matsuo, Takanori Naito, Kazuhiro Kuroda, Koji Tokioka, Kunihiko Hatanaka, Ryohei Fujimoto, Hidenaru Yamaoka, Yutaka Kajikawa, Kazuki Suruga, Hiroki Sugiyama, Tsuyoshi Miyaji, Yoshimasa Morimoto, Nobuhiro Okamura, Toshihiro Sarashina, Satoshi Akagi, Toru Miyoshi, Kazufumi Nakamura, Hiroshi Ito, Shinsuke Yuasa   +20 more
doaj   +1 more source

Early Bleeding Risk After DOAC Initiation With Concomitant Amiodarone in Older Adults With Atrial Fibrillation

Journal of Cardiovascular Electrophysiology, Volume 37, Issue 9, Page 2119-2121, September 2026.
ABSTRACT Background Amiodarone is frequently co‐prescribed with direct oral anticoagulants (DOACs) in atrial fibrillation (AF), but its impact on early bleeding risk after DOAC initiation in older adults remains uncertain. We evaluated short‐term safety outcomes associated with concomitant amiodarone use at the time of DOAC initiation.
Isadora D. Guarino, Saman Nazarian
wiley   +1 more source

Determination of Edoxaban in Bulk and in Tablet Dosage Form by Stability Indicating High-Performance Liquid Chromatography

Pharmaceutical Sciences, 2016
Background: Edoxaban is an orally active direct factor Xa inhibitor. The aim of the present study was to develop a stability indicating HPLC method for the quantification of edoxaban in bulk and in tablet dosage form. Methods: Edoxaban was separated on
Pasam Satyanarayana Reddy , V. Shanmukha Kumar Jagarlapudi, Chandra Bala Sekaran
doaj   +1 more source

Is Routine Interruption of Direct Oral Anticoagulants Necessary during Colorectal Endoscopic Mucosal Resection and Hot Snare Polypectomy? A Multicenter Propensity‐Matched Study

Journal of Gastroenterology and Hepatology, Volume 41, Issue 9, Page 2826-2833, September 2026.
ABSTRACT Background and Aims Colorectal endoscopic mucosal resection (EMR) and hot snare polypectomy (HSP) are high‐bleeding‐risk endoscopic procedures, and most clinical guidelines recommend stopping direct oral anticoagulants (DOACs) temporarily or switching to heparin‐bridging therapy (HBT). However, existing evidence is largely derived from cohorts
Yutaka Okagawa, Masanori Sato, Masahiro Hirakawa, Shogo Miura, Naotaka Hayasaka, Yusuke Tomita, Saki Ameda, Ginji Omori, Shutaro Oiwa, Akira Sakurada, Tomoyuki Abe, Shinya Minami, Tetsuya Sumiyoshi, Yasuhiro Nagaoka, Hiroyuki Hisai, Shinichi Katsuki, Kohichi Takada   +16 more
wiley   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, Volume 40, Issue 15, August 2026.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

Ex vivo reversal of the anticoagulant effects of edoxaban [PDF]

, 2014
IntroductionEdoxaban is an oral, once-daily direct factor Xa (FXa) inhibitor. Although rapidly cleared, strategies to reverse edoxaban-mediated effects on anticoagulation are needed in cases of excessive bleeding or emergency.
Halim, Abdel-Baset, Samama, Meyer M., Abdel-Baset Halim, Jeanne Mendell, Meyer M. Samama, Mendell, Jeanne   +5 more
core   +1 more source

Factor XI Inhibition for Ischemic Stroke Secondary Prevention: Pharmacology, Clinical Evidence, and Future Directions

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Ischemic stroke remains a leading cause of death and disability worldwide, and bleeding (particularly intracranial hemorrhage) continues to limit conventional antithrombotic therapy in secondary prevention, even with direct oral anticoagulants.
Federica Ferrari, Roberto Federico Villa
wiley   +1 more source

Cost-effectiveness of edoxaban versus rivaroxaban for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF) in the US

, 2016
Jeffrey D Miller,1 Xin Ye,2 Gregory M Lenhart,1 Amanda M Farr,1 Oth V Tran,1 W Jackie Kwong,2 Elizabeth A Magnuson,3 William S Weintraub41Truven Health Analytics Inc, Cambridge, MA, 2Daiichi Sankyo Inc, Parsippany, NJ, 3St Luke Mid-America Heart ...
Miller JD, Tran OV, Kwong WJ, Farr AM, Magnuson EA, Weintraub WS, Ye X, Lenhart GM   +7 more
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