Results 41 to 50 of about 5,506 (119)

CDG due to Defective Membrane Transporters: Update

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Congenital disorders of glycosylation are genetic defects in the glycoprotein and glycolipid glycan assembly and attachment. Some 200 CDG have been reported since the first clinical description in 1980. Most CDG are enzymatic deficiencies, but 13 (6.5%) are defects in the ER, Golgi apparatus (GA), and plasma membrane transporters.
D. Quelhas, C. R. Ferreira, J. Jaeken
wiley   +1 more source

LEPTOSPIROSIS AND OROPOUCHE FEVER – CASE REPORT AND LITERATURE REVIEW

Brazilian Journal of Infectious Diseases
Leptospirosis and Oropouche fever are two conditions to consider in the differential diagnosis of acute febrile illness. Leptospirosis is an endemic disease, and its severe form has high mortality (Weil’s syndrome). Oropouche fever is an emerging disease
Rodrigo Schrage Lins, Lessandra Michelin Rodriguez Lins, Luisa Saori Fujimoto Almeida, Margareth Mayumi Fujimoto, Viviane Bogado Leite Torres   +4 more
doaj   +1 more source

MicroRNA profiling of testicular Leydig cell tumors identifies a microRNA signature associated with malignancy and miR‐196b‐5p as a potentially useful biomarker

The Journal of Pathology, Volume 268, Issue 1, Page 54-64, January 2026.
Abstract Approximately 10% of testicular Leydig cell tumors (LCTs) are clinically malignant and unresponsive to systemic treatment. Predicting their clinical behavior can be problematic because there are no biomarkers that can consistently discriminate between benign and malignant LCTs.
João Lobo, Nuno Tiago Tavares, Fernanda Fernandes‐Pontes, Vera Constâncio, Ana Teixeira Marques, Bruno Oliveira‐Lopes, Diana Fonseca, Carmen Jerónimo, Rui Henrique, Kvetoslava Michalova, Kristine M Cornejo, Maurizio Colecchia, Costantino Ricci, Muhammad T Idrees, Felix Contreras, Isabel M Fernandez Gonzalez, William J Anderson, Fiona MacLean, Adeboye O Osunkoya, Chia‐Sui Kao, Ankur R Sangoi, Thomas M Ulbright, Andres M Acosta   +22 more
wiley   +1 more source

Produção científica sobre educação médica no Brasil: estudo a partir das publicações da Revista Brasileira de Educação Médica

Revista Brasileira de Educação Médica
A pesquisa em educação médica é o estudo crítico e sistemático do ensino e aprendizagem em Medicina. É um campo em crescimento, em número tanto de pesquisadores envolvidos, como de produções geradas.
Pedro Tadao Hamamoto Filho, Carlos Alberto Santos Filho, Joélcio Francisco Abbade, José Carlos Peraçoli   +3 more
doaj   +1 more source

Lipidomic profiling unveils sex differences in diabetes risk: Implications for precision medicine

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
This study uncovered sex‐specific metabolic and lipidomic signatures of prediabetes. In PREVADIAB2 (n = 953), clustering by insulin traits revealed four phenotypes. Lipidomics showed women enriched in dihydroceramides and sphingomyelins, while men displayed a higher ceramide/sphingomyelin ratio. These sex‐metabolic phenotypes expose distinct lipidomes,
Ana F. Pina, Maria João Meneses, Fabrizia Carli, Rogério T. Ribeiro, Luís Gardete‐Correia, José M. Boavida, João F. Raposo, Amalia Gastaldelli, M. Paula Macedo   +8 more
wiley   +1 more source

From Neuron‐Centric to Glia‐Centric: How Aging Glial Networks Drive Neurodegenerative Disease

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
During aging, progressive alterations in glial networks reshape intercellular communication within the central nervous system. In the young brain, astrocytes and microglia actively regulate metabolic, immune, and synaptic processes that sustain neural circuit stability.
Lívia de Sá Hayashide, Bruna Pessoa, Gustavo Dias, Bruno Pontes, Rafael Serafim Pinto, Luan Pereira Diniz   +5 more
wiley   +1 more source

Analysis of Aspergillus spp. Isolates According to Temporal–Spatial, Sociodemographic, and Clinical Variables—Microsatellite Typing of Clinical and Environmental Samples of Aspergillus fumigatus in a University Hospital in Sao Paulo, Brazil

Mycoses, Volume 69, Issue 1, January 2026.
ABSTRACT Background Typing Aspergillus species is crucial for understanding the sources of infection in hospital environments. Objectives This study analysed clinical and air samples as well as their relationship with the clinical forms of aspergillosis.
Claudia de Abreu Fonseca, Ricardo Araujo, Vivian Caso Coelho, Carlos Henrique Camargo, Marcello Mihailenko Chaves Magri, Adriana Lopes Motta, Marina Farrel Côrtes, Ana Carolina Mamana, Marjorie Vieira Batista, Daniel Valério da Silva Moreira, Ana Paula Croce, Mauro Cintra Giudice, André Nathan Costa, Sergio Eduardo Demarzo, Alexandra Gomes dos Santos, Thais Guimarães, Vera Lucia Teixeira de Freitas, Sílvia Figueiredo Costa, Maria Aparecida Shikanai Yasuda   +18 more
wiley   +1 more source

Evolução da Política de Educação Médica em Cabo Verde

Saúde e Sociedade
Resumo Cabo Verde é um dos Pequenos Estados Insulares em Desenvolvimento do mundo, com especificidades e desafios próprios. Independente há 43 anos, com meio milhão de habitantes, a formação dos seus médicos tem sido feita no exterior, incrementando a ...
Antonio Pedro Delgado, Sónia Dias, André Tolentino, Giuliano Russo, Paulo Ferrinho   +4 more
doaj   +1 more source

Treinamento por simulação em medicina: uma investigação cienciométrica de artigos indexados na Scopus [PDF]

Revista Brasileira de Educação Médica
RESUMO Introdução: O treinamento simulado (TS) na área da saúde é um método que expõe estudantes a cenários clínicos complexos em ambientes controlados, permitindo a prática e o desenvolvimento de habilidades sem risco ao paciente.
Wellington Luiz, Itamar Magalhães Gonçalves, Neila Barbosa Osório, Fernando Rodrigues Peixoto Quaresma, Erika da Silva Maciel, Luiz Sinésio Silva Neto   +5 more
doaj   +1 more source

A Systematic Review and Meta‐Analysis Comparing the Diagnostic Accuracy of Swab Cultures and Tissue Biopsy for Diagnosing Diabetic Foot Infections

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Objectives To evaluate and compare the diagnostic accuracy and concordance of swab cultures and tissue biopsy for identifying causative pathogens. Furthermore, to compare the sensitivity, specificity and overall diagnostic performance of swab cultures and tissue biopsies, using tissue biopsy as the reference standard in infected diabetic foot wounds ...
Roberto S. Heck, ⁠Rodrigo S. Lins, ⁠Daniela R. Speransa, Pedro Lopez, ⁠Lessandra Michelin, Sreeja Dattachoudhury   +5 more
wiley   +1 more source