Results 31 to 40 of about 5,366 (118)

Real‐world prevalence of PD‐L1 positivity in early‐stage/metastatic triple‐negative breast cancer: primary results and pathology insights from the global retrospective observational VANESSA study

Histopathology, Volume 88, Issue 7, Page 1373-1384, June 2026.
In the real‐world VANESSA study in triple‐negative breast cancer, PD‐L1‐positive prevalence was 38% in early‐stage and 20% in metastatic tumours, lower than in prospective trials. The lower prevalence in smaller versus larger tissue samples and by local versus central assessment underlines the importance of robust PD‐L1 testing to determine eligibility
Corrado D'Arrigo, Sitki Tuzlali, Romualdo Barroso‐Sousa, Nagi S El Saghir, Rebecca Dent, Nataša Medić‐Milijić, Gyungyub Gong, Shahin Sayed, Tu Thai Anh, Alisan Zirtiloglu, Götz Hartleben, Paula Toro, Iman Estaytieh, Enya Weber, Regula Deurloo, João Mouta, Lazar Popovic   +16 more
wiley   +1 more source

DEATH IN A YOUNG PATIENT REINFECTED WITH COVID

Brazilian Journal of Infectious Diseases
The impact of infection with SARS-CoV-2 (COVID-19) varies widely depending on individual factors such as age and associated comorbidities. We report the case of a 39-year-old man, overweight (BMI 29), who was admitted to an Intensive Care Unit in 2021 ...
Elisa Maria de Oliveira Grotti, Luciana Bonafin Francisco, Iris Ricardo Rossin   +2 more
doaj   +1 more source

Sistema de créditos. Educação médica pós-graduada e educação médica contínua.

Acta Médica Portuguesa, 1994
The author examines the objectives behind the possible adoption of a Credit System by the Portuguese Medical Association. Credits are units that allow physicians to keep a record of their educational and professional undertaking.
A M Ferreira
doaj   +1 more source

Estudos sobre a formação em pesquisa na educação médica: um estado da questão

Revista Brasileira de Educação Médica, 2022
Resumo: Introdução: É notória a crescente importância dada à formação em pesquisa na educação médica por todo o mundo, o que é refletido na crescente produção científica com essa temática.
Sarlene Gomes de Souza, Silvia Maria Nóbrega-Therrien, Pedro Mansueto Melo de Souza, Francisco Jadson Franco Moreira, Vanessa de Carvalho Forte   +4 more
doaj   +1 more source

A longitudinal network analysis of pain, psychological processes and psychological and sexual distress in women with endometriosis

British Journal of Health Psychology, Volume 31, Issue 2, May 2026.
Abstract Objectives Previous studies in endometriosis have linked the experience and impact of pain to psychological distress and sexual dysfunction. However, little is known about how these factors interact over time or how underlying cognitive‐emotional processes contribute to their complex interconnections.
Sérgio A. Carvalho, Brittany Patafio, Patrícia M. Pascoal, Teresa Lapa, David Skvarc   +4 more
wiley   +1 more source

Educación en facultades de medicina del mundo durante el periodo de contingencia por SARS-COV-2

MedUNAB, 2021
RESUMEN Introducción. La pandemia del SARS-CoV-2 se empezó a reportar desde diciembre de 2019 en la localidad de Wuhan, China, luego se presentaron miles de casos en el mundo.
Mateo Zuluaga-Gómez, Nelcy Lorena Valencia-Ortiz   +1 more
doaj   +1 more source

Genetic Ancestry Reveals Historical Diversity of Formation Across Three Brazilian Communities of African Descent (Quilombos) in Central Brazil

American Journal of Human Biology, Volume 38, Issue 1, January 2026.
ABSTRACT Introduction Characterized as relatively isolated communities, many Brazilian quilombos were formed during the period of slavery in Brazil when enslaved persons (most of African descent) ran away or were abandoned by their enslavers. Quilombos in Central Brazil, whose settlement was more recent due to the relative isolation of the region ...
Sabrina Guimarães Paiva, Anna C. Rivara, Matheus de Castro Nóbrega, Rafaela de Cesare Parmezan Toledo, Maria de Nazaré Klautau‐Guimarães, Sidney Emanuel Batista dos Santos, Lorena Madrigal, Silviene Fabiana de Oliveira   +7 more
wiley   +1 more source

NÃO ADESÃO AO TRATAMENTO DA ANEMIA FALCIFORME, UM DESAFIO EM SAÚDE PÚBLICA: RELATO DE CASO

Hematology, Transfusion and Cell Therapy, 2023
Introdução: A anemia falciforme (AF) decorre de mutações genéticas herdadas no estado homozigótico, cuja fisiopatogenia compreende eritrofalciformação, hemólise intravascular, anemia hemolítica crônica, vasculopatia proliferativa, alterações endoteliais ...
SR Souza, CC Junior, R Neder
doaj   +1 more source

CDG due to Defective Membrane Transporters: Update

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Congenital disorders of glycosylation are genetic defects in the glycoprotein and glycolipid glycan assembly and attachment. Some 200 CDG have been reported since the first clinical description in 1980. Most CDG are enzymatic deficiencies, but 13 (6.5%) are defects in the ER, Golgi apparatus (GA), and plasma membrane transporters.
D. Quelhas, C. R. Ferreira, J. Jaeken
wiley   +1 more source

TOXIC EPIDERMAL NECROLYSIS – CASE REPORT AND LITERATURE REVIEW WITH FOCUS ON ANTIMICROBIAL STEWARDSHIP

Brazilian Journal of Infectious Diseases
Introduction/Case: Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson Syndrome (SJS) are severe and rare allergic reactions, with an incidence of 1–10 cases per million people per year, differing only by the percentage of body surface area affected ...
Rodrigo Schrage Lins, Lessandra Michelin Rodriguez Lins, Luiza Saori Fujimoto Almeida, Margareth Mayumi Fujimoto, Cíntia Duarte Corrêa da Costa   +4 more
doaj   +1 more source