Results 51 to 60 of about 13,066 (159)

NÃO ADESÃO AO TRATAMENTO DA ANEMIA FALCIFORME, UM DESAFIO EM SAÚDE PÚBLICA: RELATO DE CASO

Hematology, Transfusion and Cell Therapy, 2023
Introdução: A anemia falciforme (AF) decorre de mutações genéticas herdadas no estado homozigótico, cuja fisiopatogenia compreende eritrofalciformação, hemólise intravascular, anemia hemolítica crônica, vasculopatia proliferativa, alterações endoteliais ...
SR Souza, CC Junior, R Neder
doaj   +1 more source

A longitudinal network analysis of pain, psychological processes and psychological and sexual distress in women with endometriosis

British Journal of Health Psychology, Volume 31, Issue 2, May 2026.
Abstract Objectives Previous studies in endometriosis have linked the experience and impact of pain to psychological distress and sexual dysfunction. However, little is known about how these factors interact over time or how underlying cognitive‐emotional processes contribute to their complex interconnections.
Sérgio A. Carvalho, Brittany Patafio, Patrícia M. Pascoal, Teresa Lapa, David Skvarc   +4 more
wiley   +1 more source

TOXIC EPIDERMAL NECROLYSIS – CASE REPORT AND LITERATURE REVIEW WITH FOCUS ON ANTIMICROBIAL STEWARDSHIP

Brazilian Journal of Infectious Diseases
Introduction/Case: Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson Syndrome (SJS) are severe and rare allergic reactions, with an incidence of 1–10 cases per million people per year, differing only by the percentage of body surface area affected ...
Rodrigo Schrage Lins, Lessandra Michelin Rodriguez Lins, Luiza Saori Fujimoto Almeida, Margareth Mayumi Fujimoto, Cíntia Duarte Corrêa da Costa   +4 more
doaj   +1 more source

Genetic Ancestry Reveals Historical Diversity of Formation Across Three Brazilian Communities of African Descent (Quilombos) in Central Brazil

American Journal of Human Biology, Volume 38, Issue 1, January 2026.
ABSTRACT Introduction Characterized as relatively isolated communities, many Brazilian quilombos were formed during the period of slavery in Brazil when enslaved persons (most of African descent) ran away or were abandoned by their enslavers. Quilombos in Central Brazil, whose settlement was more recent due to the relative isolation of the region ...
Sabrina Guimarães Paiva, Anna C. Rivara, Matheus de Castro Nóbrega, Rafaela de Cesare Parmezan Toledo, Maria de Nazaré Klautau‐Guimarães, Sidney Emanuel Batista dos Santos, Lorena Madrigal, Silviene Fabiana de Oliveira   +7 more
wiley   +1 more source

Knowledge and interest in medical ethics and bioethics in medical graduation

, 2008
OBJECTIVES: To evaluate the interest and knowledge about Medical Ethics and Bioethics in medical graduation. METHODS: Transversal and descriptive study.
Bitencourt, Almir Galvão Vieira, Nery-filho, Antônio, Neves, Nedy Maria Branco Cerqueira, Almeida, Alessandro de Moura, Lordelo, Marina Da Rocha [UNIFESP], Barbetta, Marcelo Campos, Neves, Flávia Branco Cerqueira Serra, Nuñez, Geila Ribeiro, Athanazio, Rodrigo Abensur [UNIFESP], Lemos, Kleuber Moreira   +9 more
core   +1 more source

CDG due to Defective Membrane Transporters: Update

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Congenital disorders of glycosylation are genetic defects in the glycoprotein and glycolipid glycan assembly and attachment. Some 200 CDG have been reported since the first clinical description in 1980. Most CDG are enzymatic deficiencies, but 13 (6.5%) are defects in the ER, Golgi apparatus (GA), and plasma membrane transporters.
D. Quelhas, C. R. Ferreira, J. Jaeken
wiley   +1 more source

Qualifications For Medical Preceptors And User Satisfaction Regarding Care Received In Their Basic Health Unit (bhu) Of Origin [PDF]

, 2017
As diretrizes curriculares propõem um perfil desejado para o médico formado, adequando o currículo às necessidades da população, com abordagem integral do indivíduo. Os profissionais da área da saúde frequentemente participam da integração ensino-serviço
Cristiane Maria Carvalho; Bicudo, Angélica Maria; Zanolli, Lopes, Maria de Lurdes   +3 more
core  

LEPTOSPIROSIS AND OROPOUCHE FEVER – CASE REPORT AND LITERATURE REVIEW

Brazilian Journal of Infectious Diseases
Leptospirosis and Oropouche fever are two conditions to consider in the differential diagnosis of acute febrile illness. Leptospirosis is an endemic disease, and its severe form has high mortality (Weil’s syndrome). Oropouche fever is an emerging disease
Rodrigo Schrage Lins, Lessandra Michelin Rodriguez Lins, Luisa Saori Fujimoto Almeida, Margareth Mayumi Fujimoto, Viviane Bogado Leite Torres   +4 more
doaj   +1 more source

MicroRNA profiling of testicular Leydig cell tumors identifies a microRNA signature associated with malignancy and miR‐196b‐5p as a potentially useful biomarker

The Journal of Pathology, Volume 268, Issue 1, Page 54-64, January 2026.
Abstract Approximately 10% of testicular Leydig cell tumors (LCTs) are clinically malignant and unresponsive to systemic treatment. Predicting their clinical behavior can be problematic because there are no biomarkers that can consistently discriminate between benign and malignant LCTs.
João Lobo, Nuno Tiago Tavares, Fernanda Fernandes‐Pontes, Vera Constâncio, Ana Teixeira Marques, Bruno Oliveira‐Lopes, Diana Fonseca, Carmen Jerónimo, Rui Henrique, Kvetoslava Michalova, Kristine M Cornejo, Maurizio Colecchia, Costantino Ricci, Muhammad T Idrees, Felix Contreras, Isabel M Fernandez Gonzalez, William J Anderson, Fiona MacLean, Adeboye O Osunkoya, Chia‐Sui Kao, Ankur R Sangoi, Thomas M Ulbright, Andres M Acosta   +22 more
wiley   +1 more source

Lipidomic profiling unveils sex differences in diabetes risk: Implications for precision medicine

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
This study uncovered sex‐specific metabolic and lipidomic signatures of prediabetes. In PREVADIAB2 (n = 953), clustering by insulin traits revealed four phenotypes. Lipidomics showed women enriched in dihydroceramides and sphingomyelins, while men displayed a higher ceramide/sphingomyelin ratio. These sex‐metabolic phenotypes expose distinct lipidomes,
Ana F. Pina, Maria João Meneses, Fabrizia Carli, Rogério T. Ribeiro, Luís Gardete‐Correia, José M. Boavida, João F. Raposo, Amalia Gastaldelli, M. Paula Macedo   +8 more
wiley   +1 more source