Results 31 to 40 of about 4,330 (134)

Habilidades socioemocionales: alumnos con discapacidad visual en un aula inclusiva de educación infantil

INFAD, 2021
La educación socioemocional en niños y niñas con discapacidad visual es un derecho humano, cuyo objetivo es garantizar esta educación de calidad en igualdad de oportunidades con una perspectiva de equidad.
Wendy Itzameny Cahum González, Maricela Zuñiga Rodríguez   +1 more
doaj   +1 more source

Plasma Aβ40, Aβ42, Aβ42/40 ratio, tau, p‐tau181, p‐tau217 and NfL biomarkers to discriminate the prodromal stage of dementia along the continuum of cognitive impairment: Sex differences in the CompAS study [PDF]

Alzheimers Dement
Abstract Background Plasma Aβ40, Aβ42, Aβ42/40 ratio, tau, p‐tau181, p‐tau217, and NfL have been proposed as possible valid early blood biomarkers for Alzheimer's Dementia (AD) (Simren et al., 2021). Although sex differences in some biomarkers (e.g., p‐Tau‐181) were suggested in some studies (Tsiknia et al., 2022), this issue remains largely unexplored.
Rodríguez‐Pérez A, Ansede‐Bermejo J, Lojo‐Seoane C, Campos‐Magdaleno M, Nieto‐Vieites A, Felpete A, Galdo‐Álvarez S, Lindín M, Rojo‐Pantoja Á, Moreno‐Carretero M, Aldrey J, Spuch C, Pías‐Peleteiro J, Carracedo A, Labandeira J, Zurrón M, Facal D, Díaz F, Rozas A.   +18 more
europepmc   +2 more sources

Perceived Threat of COVID‐19 and Vaccination Coverage Among Nurses: A Multicentre Cross‐Sectional Study

Nursing Open, Volume 13, Issue 3, March 2026.
ABSTRACT Aim Analyse the perceived threat of COVID‐19, vaccination coverage and associated factors among nurses in Barcelona (Spain) in 2021 after the start of the vaccination campaign. Design Multicentre cross‐sectional study using an anonymous online questionnaire accessible from 26 February to 31 May 2021. Cherries guidelines were followed.
Marina Moreno‐Martínez, Maria Feijoo‐Cid, Josep Maria Manresa‐Dominguez, Antonia Arreciado Marañón, Esperanza Zuriguel‐Pérez, Sandra Ponce‐Ruíz, Ramón Sebastián Torrente‐Jimenez, Maria Isabel Fernández‐Cano   +7 more
wiley   +1 more source

Generation of functional noncanonical donor splice sites by +2T variants in breast cancer susceptibility genes: impact on clinical interpretation

The Journal of Pathology, Volume 268, Issue 2, Page 150-163, February 2026.
Abstract Splicing dysregulation is a relevant mechanism of pathogenicity for variants in disease susceptibility genes. Variants affecting the critical intronic +1 and +2 GT nucleotides of the 5’ splice sites (5'ss) are generally strong indicators of pathogenicity.
Inés Llinares‐Burguet, Lara Sanoguera‐Miralles, Elena Bueno‐Martínez, Alicia García‐Álvarez, Alberto Valenzuela‐Palomo, Pedro Pérez‐Segura, Miguel de la Hoya, Eladio A Velasco‐Sampedro   +7 more
wiley   +1 more source

A Multidomain Lifestyle Intervention Is Associated With Improved Functional Trajectories and Favorable Changes in Epigenetic Aging Markers in Frail Older Adults: A Randomized Controlled Trial

Aging Cell, Volume 25, Issue 2, February 2026.
In frail older adults, a 6‐month lifestyle intervention slowed epigenetic aging and improved functional outcomes, suggesting lifestyle strategies may delay biological aging and disability progression. ABSTRACT Frailty emerges as the intermediate stage preceding disability, but there is a gap in molecular signatures for early detection of subclinical ...
Gloria Olaso‐Gonzalez, Fernando Millan‐Domingo, Luis Garcia‐Fernandez, Elisa Garcia‐Tercero, Monica Cebrian, Cristina Garcia‐Dominguez, Juan Antonio Carbonell, German Casabo‐Valles, Jose Luis Garcia‐Gimenez, Eva Tamayo‐Torres, Juan Gambini, Francisco Jose Tarazona‐Santabalbina, Jose Vina, Maria Carmen Gomez‐Cabrera   +13 more
wiley   +1 more source

Cambios en la ingesta de sal y práctica de ejercicio físico en pacientes hipertensos por educación sanitaria en el primer nivel de atención de salud

Revista Médica Herediana, 2013
Aunque se asume que la educación sanitaria mejora los estilos de vida de los pacientes hipertensos, no existe suficiente bibliografía que apoye esta asociación.
Arturo Gabriel Jurado-Vega
doaj  

Examen al Egreso de la Educación Básica en el Área de Salud (EXEEBAS): Análisis de unidimensionalidad

Revista Complutense de Educación, 2017
Dentro del currículum mexicano se ha incluido la salud como uno de los once temas de relevancia social. Los temas que intentan formar a los estudiantes mexicanos en la cultura de la salud, se encuentran diseminados a lo largo del currículum de la ...
Valeria Cantú González, Juan Carlos Rodríguez Macías   +1 more
doaj   +1 more source

Optochemical modulation of corneal cold nerve terminal impulse activity with a photochromic ion channel blocker

British Journal of Pharmacology, Volume 183, Issue 3, Page 545-559, February 2026.
Background and Purpose The functional organization of corneal cold nerve endings, critical structures in maintaining the ocular surface, remains poorly understood. Here, the photoisomerizable small‐molecule diethylamine‐azobenzene‐quaternary ammonium (DENAQ) was used to photomodulate activity of cold‐sensing nerve terminals in control and chronic tear ...
David Ares‐Suárez, Almudena Iñigo‐Portugués, Enrique Velasco, Susana Quirce, Fernando Aleixandre‐Carrera, Ariadna Díaz‐Tahoces, M. Carmen Acosta, Wan‐Chen Lin, Richard H. Kramer, Carlos Belmonte, Juana Gallar, Victor Meseguer   +11 more
wiley   +1 more source

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

Advanced Materials, Volume 38, Issue 2, 8 January 2026.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal, Sandra Clara‐Trujillo, Elena Lucena‐Sánchez, Francisco J. Hicke, Andrea Escudero, Sandra Pradana‐López, Nelia Jiménez‐Alduan, Paula Díez, Alba García‐Fernández, Ramón Martínez‐Máñez   +9 more
wiley   +1 more source

Synthesis of Benzopyrans and Quinolines with Nitrogenated Chain and Their Cytotoxicity Against Human Cancer Cell Lines

ChemMedChem, Volume 21, Issue 2, January 2026.
Natural products and/or their structural analogs represent the greatest number of approved small‐molecules as antitumor agents. We report the synthesis of 2‐propanamide and 2‐propanamine dihydrobenzopyrans and 2‐ and 2,3‐disubstituted quinolines to evaluate their cytotoxicity against human A549 (lung), A2058 (melanoma), HepG2 (liver), MCF‐7 (breast ...
Bernabeu‐Sanchis Álvaro, Thomas A. Mackenzie, Maria C. Ramos, Ainhoa García, Carlos Villarroel‐Vicente, Laura Vila, José R. Tormo, Diego Cortes, Nuria Cabedo   +8 more
wiley   +1 more source