Results 31 to 40 of about 4,491 (135)

Functional assessment of inherited myeloid neoplasm‐associated SAMD9L germline variants via Monoallelic CRISPR modelling

British Journal of Haematology, EarlyView.
Summary While the majority of myeloid neoplasms are sporadic, the increasing application of germline genetic testing has led the World Health Organization to designate ‘Myeloid malignancies with germline predisposition’ as a distinct clinical entity, carrying major implications for clinical care and research.
Elena Vuelta, Alessandro Liquori, Matias Morín, Lucia Soletto, Miguel Ángel Marugal, Marta Santiago‐Balsera, Miguel Gallardo, Miguel Ángel Moreno‐Pelayo, José Cervera, Alejandra Sanjuan‐Pla   +9 more
wiley   +1 more source

Manejo de los inhaladores en pacientes bronquíticos

Anales del Sistema Sanitario de Navarra, 2009
En la Unidad de Medicina Interna ingresan un alto porcentaje de pacientes con patología respiratoria, principalmente EPOC. La base del tratamiento del paciente con obstrucción crónica de vías aéreas son los broncodilatadores y corticoides administrados ...
E. Berrade, S. Torrea
doaj   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, Volume 183, Issue 18, Page 5458-5475, September 2026.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

Educación sanitaria en el paciente trasplantado renal: una revisión integrativa

Enfermería Nefrológica
Introducción: La fase más avanzada de la enfermedad renal crónica avanzada, requiere tratamiento renal sustitutivo, siendo el trasplante renal una opción destacada debido a sus beneficios.
Raquel Espejo Rodríguez, Carmen Morales Cuenca, Antonio José Martín Hurtado, Rodolfo Crespo Montero   +3 more
doaj   +1 more source

Estudio sobre los conocimientos de hanseníase que tienen los trabajadores de salud

Hansenologia Internationalis, 2000
La educación sanitaria en lepra se considera fundamental en la estrategia de trabajo, para alcanzar la meta de eliminación lanada por la O.M.S. (Organización Mundial de la Salud.) para el ano 2000.
Silvia N. Paredes, Cristina Cuello, Mónica Prida   +2 more
doaj   +1 more source

Salud planetaria: educación para una atención sanitaria sostenible

Educación Médica, 2021
Resumen: Los «Objetivos para el desarrollo sostenible 2030» marcan la necesidad de una educación para el desarrollo sostenible que logre mantener la salud planetaria.
Cristina Álvarez-García, Isabel María López-Medina, Sebastián Sanz-Martos, Carmen Álvarez-Nieto   +3 more
doaj   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1129-1140, June 2026.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Predicting cognitive worsening using subjective reports of dyads and biological biomarkers in pre‐clinical stages: Preliminary results from the CompAS cohort study [PDF]

Alzheimers Dement
Abstract Background The utility of cognitive complaints and biological biomarkers as a factor risk of dementia among cognitively unimpaired individuals is not yet clear (Nosheny et al., 2022). Our aim was to study the joint contribution of subjective reports and some plasma biomarkers to predict cognitive worsening from preclinical stages.
Pérez‐Blanco L, Rodríguez‐Pérez A, Felpete A, Nieto‐Vieites A, Fernández‐Feijoo F, Lojo‐Seoane C, Juncos‐Rabadán O, Facal D, Rozas A.   +8 more
europepmc   +2 more sources

“Humanizar”: aprendizajes sobre alteridad, salud y futuro en una experiencia de investigación compartida

The Journal of Latin American and Caribbean Anthropology, Volume 31, Issue 2, June 2026.
ABSTRACT The visit to Bogotá of a fééeneminaa (Muinane) friend, Célimo Nejedeka Jifichíu, and in particular, his work in researching and transmitting traditional health knowledge, offer the pretext to navigate the relationship between elements that at first glance seem distant from each other: indigenous imaginaries about otherness, their visions of ...
Giovanna Micarelli
wiley   +1 more source

Unveiling nuclear localization signals in human arginine deiminase proteins

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Arginine iminohydrolases are a family of enzymes involved in the conversion of arginine to citrulline. There are five isoforms in humans (PADI1, 2, 3, 4, and 6). Some of them are observed experimentally in the cytoplasm and in the nucleus of the cell; for moving to the latter location, they must pass through the cell nuclear membrane by using ...
José L. Neira, Olga Abian, Adrián Velazquez‐Campoy, Bruno Rizzuti   +3 more
wiley   +1 more source