Results 81 to 90 of about 525,680 (314)

The Role of Alaska's Nurse Practitioners in Preventing Early Childhood Caries [PDF]

open access: yes, 2014
Early Childhood Caries (ECC) is the most common chronic disease of childhood despite being preventable. Because of its high prevalence, its impact on the quality of life of young children, and its potential for increasing their risk of caries in the ...
Maixner, Margaret
core  

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

open access: yesAdvanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen   +11 more
wiley   +1 more source

Dental education in Peru

open access: yesJournal of Oral Science, 2008
This paper provides information about Peru's dental history and dental school system, including the curriculum and dental licensure. With the increase in the number of dental schools in Peru, the number of dentists is also increasing. Until 1965, Peru had only three dental schools; currently, there are 14.
Takashi, Komabayashi   +4 more
openaire   +3 more sources

Clinical Impact of a Novel Interprofessional Dental and Pharmacy Student Tobacco Cessation Education Program on Dental Patients [PDF]

open access: yes, 2016
Objectives: • To compare the difference between IPE care and standard care (SC) groups regarding dental patients\u27 perceptions of knowledge gained about tobacco cessation, intentions to quit tobacco use, and quit attempts at follow-up.
Boyd, PharmD Candidate, Matthew   +5 more
core   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

open access: yesAdvanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang   +3 more
wiley   +1 more source

Dental Education in Europe [PDF]

open access: yesEuropean Journal of Dentistry, 2009
Modern dental education has its roots in the USA where the first dental school started in Baltimore in 1840. It did not take long, however, before independent dental curricula were introduced in Europe leading to different patterns of education. During the last thirty years different activities in harmonization of European higher education have lead ...
openaire   +2 more sources

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

open access: yesAdvanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl   +27 more
wiley   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

LIMITATIONS IN DENTAL EDUCATION. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1900
In dealing with limitations in dental education, we are brought face to face with their greatest evil—di-divorcement of dental from medical teaching. Removal of a special department from general medicine and tuition along narrow lines have so narrowed teaching that even diseases of the general system which affect the mouth, jaws and teeth are excluded.
openaire   +2 more sources

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason   +12 more
wiley   +1 more source

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