Results 41 to 50 of about 27,861 (215)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Anadolu Üniversitesi Eğitim Fakültesi dergisiThe aim of this research is to reveal the status of academic advising in graduate education in the field of classroom teaching. In this regard, it aims to examine the perceptions of academics and graduate students regarding the phenomenon of academic ...
Sayım Aktay, Esadiye Pekdemir
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
BMC Medical EducationBackground Graduate nursing education is the main way to train high-quality nursing personnel. Globally, the nursing education system has been gradually improved, forming a multi-level, multi-channel, and multi-specification education system including ...
Caini Song +3 more
doaj +1 more source
Integrative reviews in Brazilian nursing postgraduation programs: a bibliometric study [PDF]
Revista Brasileira de EnfermagemObjectives: to analyze the Brazilian scientific integrative review production in postgraduation nursing programs. Methods: bibliometric design, carried out in the database of dissertations and theses of the Coordination for the Improvement of Higher ...
Tábata Cerqueira Nascimento Nobre +2 more
doaj +4 more sources
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Status quo and countermeasures of graduate education of nursing master degree in China
Huli yanjiu, 2017 It introduced graduate education of nursing master degree in China systematically from the aspects of training objectives,recruitment,professional setting,curriculum setting,clinical practice,evaluation index system,teachers resource,students’core ...
李鹏 +4 more
doaj
Perceived factors influencing students to drop out of a post-graduate programme
Interdisciplinary Journal of Education ResearchSome post-graduate students of Agricultural Education enrolled in Master's degree programmes in Eswatini do not graduate. Unfortunately, no study has been conducted on the factors contributing to the dropout rates among these graduate students. Therefore,
Thabsile Welile Dlamini +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source