Results 51 to 60 of about 7,361,427 (296)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Revista Brasileira de Geriatria e GerontologiaO objetivo deste artigo foi identificar, com base na literatura, como a saúde do idoso e o envelhecimento têm sido abordados na formação universitária dos profissionais de saúde e o que vem sendo considerado relevante nesta temática.
Claudia Reinoso Araujo de Carvalho +1 more
doaj +1 more source
Higher education stimulating creative enterprise [PDF]
, 2011 This report summarises the research undertaken by the Business & Community School at the University for the Creative Arts (UCA), analysing ways that higher ediucation (HEIs) can support, and indeed stimulate, the creative economy.
Campbell, Frances, Ely, Philip
core +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Machine learning in coronary heart disease prediction: Structural equation modelling approach
Cogent Engineering, 2020 This research is an application of machine learning in medical sciences. The purpose of this research was to use machine learning through the simulated data to study the association of age, body mass index, cigarettes smoked per day, alcohol consumed per
Lewlyn L. R. Rodrigues +7 more
doaj +1 more source
SOA services in higher education [PDF]
, 2008 Service Oriented Architecture (SOA) is a recent architectural framework for distributed software system development in which software components are packaged as Services.
Joy, Mike +1 more
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Optimized trapezoidal-shaped hip implant for total hip arthroplasty using finite element analysis
Cogent Engineering, 2020 Hip implants consist of a stem, femoral head, acetabular cup, and backing cup. There is a wide variety of sizes and lengths. Their adaptability is limited because of the inter-anatomical variations.
Chethan K N +3 more
doaj +1 more source
Some Thoughts on Framing the Work on the Commission and the National Dialog (1) [PDF]
, 2005 http://deepblue.lib.umich.edu/bitstream/2027.42/89323/1/2005_Spelings_Commission_Framing_Paper ...
Department of Education, Secretary of Education's Commission on the Future of Higher Education
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source