Results 161 to 170 of about 831,801 (314)

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun   +14 more
wiley   +1 more source

Neutrophil/Lymphocyte Ratio as a Predictive Biomarker of NIV Failure in AECOPD: The Unveiled Facts [Letter]

open access: yesInternational Journal of COPD
Dipasri Bhattacharya,1 Antonio M Esquinas,2 Mohanchandra Mandal3 1Department of Anaesthesiology, Pain Medicine and Critical Care, R.G.Kar Medical College & Hospital, Kolkata, West Bengal, India; 2Critical Care Specialist and Staff Physician ...
Bhattacharya D, Esquinas AM, Mandal M
doaj  

Sleep Deprivation Activates a Conserved Lactate‐H3K18la‐RORα Axis Driving Neutrophilic Inflammation Across Species

open access: yesAdvanced Science, EarlyView.
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou   +15 more
wiley   +1 more source

Framing resident perceptions of diversity in GME: insights from a multi-specialty survey study. [PDF]

open access: yesBMC Med Educ
Ngankam D   +5 more
europepmc   +1 more source

Gender Bias in Resident Assessment in Graduate Medical Education: Review of the Literature

open access: yesJournal of general internal medicine, 2019
Robin Klein   +9 more
semanticscholar   +1 more source

Targeting Neutrophil/Eosinophil Extracellular Traps by Aptamer‐Functionalized Nanosheets to Overcome Recalcitrant Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao   +13 more
wiley   +1 more source

Probing Anisotropic Quasiparticle Dynamics and Topological Phase Transitions in Quasi‐1D Topological Insulator ZrTe5

open access: yesAdvanced Science, EarlyView.
This study reveals quasiparticle dynamics in ZrTe5. Polarization‐dependent measurements show transient reflectivity anisotropy arises from electron relaxation and lattice vibrations. The first dynamical evidence of a temperature‐induced Lifshitz transition is reported.
Yueying Hou   +14 more
wiley   +1 more source

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