Results 171 to 180 of about 831,801 (314)

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light‐Triggered Pyroptosis Via an Antibody‐Indocyanine Green Conjugate

Advanced Science, EarlyView.
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen, Xue‐Fei Tian, Teng Yang, Yu‐Jie Dai, Da‐Yuan Chen, Hong‐Bo Chen, Takaya Shimura, Xin‐Fang Li, Chu‐Lin Sha, Qing Ji, Jun Cao, Mei‐Yu Fang, Jin‐Biao Shang, Jian‐Min Fang, Ye Lu, Wei‐Hui Zheng, Peng Guo, Wei‐Hong Tan   +17 more
wiley   +1 more source

Revisiting the Gateway Drug Hypothesis for Cannabis: A Secondary Analysis of a Nationwide Survey Among Community Users in Japan. [PDF]

Neuropsychopharmacol Rep
Masataka Y, Katayama M, Umemura F, Sugiyama T, Miki N, Akahoshi Y, Oka C, Asahi T, Matsumori T, Takumi I, Murata H, Matsumoto T.   +11 more
europepmc   +1 more source

High‐Performing Clean Water Production by Rational Design of Functional Solar Evaporator and Vapor Condensation

Advanced Science, EarlyView.
An invert‐structured vapor condensation device coupled with solar evaporators featuring special vertically aligned vapor diffusion channels is developed to target both high evaporation and water collection rates. By minimizing the optical loss caused by condensed water and speeding up the dropwise condensation process, it achieves a record‐high water ...
Bingxing Wu, Xiangqian Fan, Chaorui Xue, Qing Chang, Jinlong Yang, Shengliang Hu, Haolan Xu   +6 more
wiley   +1 more source

The Orphaned Resident and Graduate Medical Education Program Closures. [PDF]

J Grad Med Educ
Keneally RJ, Frazier HA.
europepmc   +1 more source

A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness

Advanced Science, EarlyView.
This study identifies a sub‐circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub‐circuit is labeled by the clock output molecule mWAKE, which suppresses its excitability in a time‐dependent manner. mWAKE‐expressing cells in the SCN (SCNmWAKE cells) project to the subparaventricular zone (SPZ) to mediate ...
Qiang Liu, Sang Soo Lee, Jiali Xiong, Shahin Ahmadi, Benjamin J. Bell, Mehmet F. Keles, Mark N. Wu   +6 more
wiley   +1 more source

Race and Ethnicity: What Graduate Medical Education Programs Should Know About the Physician Data Initiative's Data Collection and Reporting Standard. [PDF]

J Grad Med Educ
Ortega P, Bauschke R, McDade W.
europepmc   +1 more source

Targeting eRNA‐Producing Super‐Enhancers Regulates TNFα Expression and Mitigates Chronic Inflammation in Mice and Patient‐Derived Immune Cells

Advanced Science, EarlyView.
Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho, Su Min Kim, Jiyeon Lee, Oh Chan Kwon, Wonjin Woo, Eunji Lee, Hyo Jin Park, Yeongun Lee, So Hee Dho, Tae‐Kyung Kim, Min‐Chan Park, Richard A. Flavell, Lark Kyun Kim   +12 more
wiley   +1 more source

Development and validation of an innovation competence instrument for medical mentors in China: a mixed-methods study. [PDF]

BMC Med Educ
Chen G, Wu J, Ni Q, Mao X, Wang YC, Yue JJ.   +5 more
europepmc   +1 more source

A Systematic Review of Advocacy Curricula in Graduate Medical Education

Journal of general internal medicine, 2019
B. Howell, R. Kristal, L. Whitmire, Mark Gentry, Tracy L. Rabin, J. Rosenbaum   +5 more
semanticscholar   +1 more source

Harnessing Work Function Modulation for Hydrogen Evolution Catalysis in Mesoporous Bimetallic Pt‐M Alloys: The Role of Mesopores in Work Function Optimization

Advanced Science, EarlyView.
This study presents mesoporous binary Pt‐M alloy films (m‐Pt‐M, M = Pd, Rh, and Ru) with uniform porosity and tailored work functions (WFs) as an experimental study platform. The WFs of the m‐Pt‐M films exhibit a volcano‐type relationship with their HER performance.
Lei Fu, Yunqing Kang, Ho Ngoc Nam, Kaiteng Wang, Zilin Zhou, Yingji Zhao, Quan Manh Phung, Kai Wu, Yusuke Asakura, Jun Zhou, Yusuke Yamauchi   +10 more
wiley   +1 more source