Results 191 to 200 of about 831,801 (314)

Dual‐Ionic Weakly Solvating Electrolyte Design Enables Efficient Fast‐Cycling of High‐Voltage Anion Shuttle Batteries

open access: yesAdvanced Science, EarlyView.
A dual‐ionic weakly solvating electrolyte is developed to simultaneously regulate cation and anion transport in sodium‐based anion shuttle batteries. Functionalized nano‐graphene oxide additives reshape solvation environments, enabling high‐rate performance and long‐term stability.
Jieun Kang   +11 more
wiley   +1 more source

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

open access: yesAdvanced Science, EarlyView.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li   +6 more
wiley   +1 more source

Contribution of Prostaglandin E2‐Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative

open access: yesAdvanced Science, EarlyView.
Glioblastoma (GBM) is an aggressive brain cancer that often recurs and resists chemotherapy. This study found that a chemical called PGE2 causes surrounding brain cells (neurons) to become over‐excited, which makes GBM cells resistant to treatment. Researchers developed a new drug, “Compound 11,” which can cross into the brain and effectively block ...
Chih‐Jie Shen   +14 more
wiley   +1 more source

The Optimizing Whiteboard Lectures (OWL) Checklist: A Novel "Chalk Talk" Assessment Tool. [PDF]

open access: yesJ Grad Med Educ
Nelson RE   +5 more
europepmc   +1 more source

Inductive‐Associative Meta‐learning Pipeline with Human Cognitive Patterns for Unseen Drug‐Target Interaction Prediction

open access: yesAdvanced Science, EarlyView.
Predicting unseen drug‐target interactions is challenging. BioBridge presents an Inductive‐Associative pipeline inspired by scientists' workflow. It combines transferable binding principles, learned via multi‐level encoders and adversarial training, with insights from weakly related references through meta‐learning.
Xiaoqing Lian   +11 more
wiley   +1 more source

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