Results 211 to 220 of about 1,165,379 (311)

Aloe‐Emodin Targeting FOXC2 Disrupts NETs Formation and EMT‐Driven Postoperative Peritoneal Adhesion Through TGF‐β1‐Smad2/3 Pathway

open access: yesAdvanced Science, EarlyView.
Forkhead box protein C2 (FOXC2) is highlighted as a pivotal effector in postoperative peritoneal adhesion (PPA) formation. Mechanically, FOXC2 mediates NETs‐induced EMT alterations through the TGF‐β1‐Smad2/3 pathway. Aloe‐emodin (AE) ameliorates FOXC2‐driven fibrosis by blocking NETs formation and EMT changes through this pathway.
Lili Yang   +10 more
wiley   +1 more source

Methods for Studying Bias in Graduate Medical Education. [PDF]

open access: yesPRiMER
Terry DL, Graham J, Terry CP, Telge M.
europepmc   +1 more source

Lactate‐Modulating Nanoreactors Facilitate Self‐Amplifying Pyroptosis and the cGAS‐STING Cascade for Potentiated Catalytic‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
An intelligent lactate‐depleting LOCoF2 (CoF2@LOx) nanoreactor system is developed to effectively induce self‐reinforced pyroptosis and activate the cGAS‐STING signaling pathway, thereby inducing a strong immune response and enhancing the therapeutic effectiveness of catalytic immunotherapy.
Linzhu Zhang   +10 more
wiley   +1 more source

Electric‐Field Control of Low Damping Constant in Epitaxial Co2FeSi/LiNbO3 Multiferroic Heterostructures

open access: yesAdvanced Science, EarlyView.
The development of multiferroic heterostructures with a half‐metallic property is one of the key technologies for electric‐field operatable magnonic devices. In this study, Co2FeSi/LiNbO3 multiferroic heterostructures with a low damping constant are experimentally developed and an electric‐field modulation of its magnetization dynamics is demonstrated.
Shinya Yamada   +7 more
wiley   +1 more source

Photopolymerized Mixed Matrix Membranes for Liquid Organic Hydrogen Carrier Separation

open access: yesAdvanced Science, EarlyView.
Photopolymerized membranes with high metal organic framework (MOF)/Pd activated carbon loading enable selective separation of hydrogen‐rich/lean liquid organic hydrogen carriers (LOHCs) under mild operational conditions. The employed fabrication approach yields stratified, multilayer structures with enhanced aromatic/aliphatic (toluene ...
Abdollah Khosravanian   +8 more
wiley   +1 more source

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

open access: yesAdvanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama   +17 more
wiley   +1 more source

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