Results 101 to 110 of about 1,732,170 (258)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Experts' consensus over key components of online learning environments in medical education: a modified e-Delphi study

Khyber Medical University Journal
Objective: To achieve expert consensus on the essential components for effective online learning environments in medical education using a modified e-Delphi approach.
Noor-i-Kiran Naeem, Siti Nurma Hanim Hadie, Irwan Mahazir Ismail, Zil-e-Fatima Naeem, Ahmad Hassan Khan, Muhamad Saiful Bahri Yusoff   +5 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Position of the advisory and executive board of the German Association for Medical Education (GMA) regarding the “masterplan for medical studies 2020”

GMS Journal for Medical Education, 2019
German Association for Medical Education GMA, Advisory Board
doaj   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Assessing Digital Competence Among Health Science Undergraduates: a Critical Analysis

Revista de Investigación e Innovación en Ciencias de la Salud
Introduction. Strategic management between the educational realm and technology is possible as long as teachers and students have adequate and timely development of digital competencies. Although current generations are receptive to technology, academic
Antonieta Herrera-Lillo, Gabriela Urrejola-Contreras   +1 more
doaj   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

The training of the medical students of Guantánamo for the radiological diagnosis of respiratory diseases

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Background: the graduation of a competent general practitioner is a social requirement. Among his competences the physician must know how to make the radiology diagnosis of respiratory diseases.Objective: to devise a system of activities to foster the ...
Reinaldo Elias-Sierra, Karla Sucet Elias-Armas   +1 more
doaj  

Understanding the consequence of COVID-19 on undergraduate medical education: Medical students' perspective. [PDF]

Ann Med Surg (Lond), 2020
Sani I, Hamza Y, Chedid Y, Amalendran J, Hamza N.   +4 more
europepmc   +1 more source