Results 61 to 70 of about 4,323,358 (286)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Sistemas de microscopía virtual: análisis y perspectivas

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2011
Desde finales del siglo XX la microscopía se ha venido transformando, incluyendo nuevos recursos que mejoran y perfeccionan su práctica. Entre ellos se destaca el microscopio virtual, la sinergia entre disciplinas como la patología, la histología, la ...
Diana Marín, Eduardo Romero
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

MEDICAL EDUCATION. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1901
n ...
openaire   +2 more sources

Medical education and the 21st century [PDF]

open access: yes, 1994
Medical education at both the undergraduate and postgraduate levels has been undergoing continuous changes in the last 40 years. The author why future Maltese doctors should continue with their medical education and have the opportunity to specialize in ...
Fenech, Frederick F.
core  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Prerequisite for Enhancing Student Learning Outcomes in Medical Education

open access: yesSultan Qaboos University Medical Journal, 2009
Anyone achieving a grade of “A” has performed at a very good level. The label, “triple A”, is sometimes used to distinguish those who are particularly outstanding.
C B Hazlett
doaj  

Rendimiento académico de estudiantes de Medicina en la asignatura Sistemas cardiovascular, respiratorio, digestivo y renal

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Fundamento: a tres años de instaurada la asignatura Sistemas cardiovascular, respiratorio, digestivo y renal (CARDIREN), del plan de estudio D, es posible caracterizar el rendimiento académico de los estudiantes en la misma.Objetivo: caracterizar el ...
Yunelsy Ortiz-Cabrera   +4 more
doaj  

MEDICAL EDUCATION. [PDF]

open access: yesThe Lancet, 1880
n ...
openaire   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

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