Results 71 to 80 of about 1,726,771 (283)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Elements of a didactic program to teach an optional course on COVID-19 in dentistry

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: the pandemic caused by COVID-19 demands that future dental professionals acquire the necessary knowledge, always keeping in mind the student diversity, allowing them to contribute to the prevention and control of the disease.Objective: to ...
Taimí Santos-Velázquez
doaj  

Strengths of the medicine degree for the formation of the professional life project in times of COVID-19

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021
Background: the complex epidemiological situation that exists worldwide, caused by COVID-19, results in changes in teaching processes.Objective: to elaborate theoretical-methodological considerations on the strengths of the medicine degree for the ...
Solvey del-Río-Marichal   +1 more
doaj  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Enhancing Medical Education with AI-Generated Visual Art: Benefits and Challenges [PDF]

open access: yesIranian Journal of Medical Sciences
Artificial intelligence (AI) has revolutionized traditional practices in different disciplines, including medical education.
Manica Negahdaripour   +2 more
doaj   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Best Practices in Patient Education: Medical Students' Perceptions and Implementations. [PDF]

open access: yesMed Sci Educ, 2023
Croniger B   +4 more
europepmc   +1 more source

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