Results 71 to 80 of about 69,764 (234)

Dimethyl Itaconate Alleviates Escherichia coli‐Induced Endometritis Through the Guanosine‐CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae

Advanced Science, EarlyView.
The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He, Jiapei Cai, Xufeng Xie, Xinyu Zhang, Linkai Qu, Jiuxi Liu, Yongguo Cao   +6 more
wiley   +1 more source

Veterinary Medical Students’ Perceptions, Attitude and Knowledge about Antibiotic Resistance and Stewardship: How Prepared Are Our Future Prescribers?

Notulae Scientia Biologicae, 2018
A cross sectional, multicentre survey utilizing a questionnaire was used to assess 6th- (final-) year veterinary medical students’ perceptions, attitude and knowledge about antibiotic resistance (ABR) and stewardship (ABS) in 5 conveniently-selected ...
Madubuike Umunna ANYANWU, Onyinye Jane OKORIE-KANU, Chidiebere Ohazuruike ANYAOHA, Oluwatosin Ajoke KOLADE   +3 more
doaj   +1 more source

Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

Advanced Science, EarlyView.
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li, Zhongyun Xie, Mengmeng Wang, Shuke Nie, Zhengjiang Qian, Xin Meng, Xia Liu, Seong Su Kang, Keqiang Ye   +8 more
wiley   +1 more source

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

Advanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang, Ruqing Zhong, Miao Zhou, Kai Li, Huiyuan Lv, Huixin Wang, Ye Xu, Dadan Liu, Qiugang Ma, Liang Chen, Hongfu Zhang   +10 more
wiley   +1 more source

Effect of binocular disparity on learning anatomy with stereoscopic augmented reality visualization: A double center randomized controlled trial

Anatomical Sciences Education, Volume 16, Issue 1, Page 87-98, January/February 2023., 2023
Abstract Binocular disparity provides one of the important depth cues within stereoscopic three‐dimensional (3D) visualization technology. However, there is limited research on its effect on learning within a 3D augmented reality (AR) environment. This study evaluated the effect of binocular disparity on the acquisition of anatomical knowledge and ...
Katerina Bogomolova, Marc A. T. M. Vorstenbosch, Inssaf El Messaoudi, Micha Holla, Steven E. R. Hovius, Jos A. van der Hage, Beerend P. Hierck   +6 more
wiley   +1 more source

RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development

Advanced Science, EarlyView.
The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao, Tianxiang Tang, Bowen Wang, Shengfei He, Yue Zhang, Li Dong, Bo Xu, Ying Liu, Ping Zhu, Rui Guo   +9 more
wiley   +1 more source

Identification of histological threshold concepts in health sciences curricula: Students' perception

Anatomical Sciences Education, Volume 16, Issue 1, Page 171-182, January/February 2023., 2023
Abstract Students' metacognitive skills and perceptions are considered important variables for high‐quality learning. In this study, students' perceptions were used to identify histological threshold concepts (integrative, irreversible, transformative, and troublesome) in three health sciences curricula.
Miguel A. Martin‐Piedra, Salvador Saavedra‐Casado, Antonio Santisteban‐Espejo, Fernando Campos, Jesus Chato‐Astrain, Oscar Dario Garcia‐Garcia, David Sanchez‐Porras, Juan de Dios Luna del Castillo, Ismael Angel Rodriguez, Antonio Campos   +9 more
wiley   +1 more source

An Interview with Dr. Steve Budsberg

Veterinary Evidence, 2016
Veterinary Evidence Editor-in-Chief Rich Evans caught up with long-time EBVM advocate Dr. Steve Budsberg at this year’s American College of Veterinary Surgeons Symposium and took the opportunity to ask Dr.
Richard Evans
doaj   +1 more source

Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma

Advanced Science, EarlyView.
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi, Kristin Huntoon, Yifan Wang, Adam Woodward, Abin Antony, Connor Endsley, Nazia Hafeez, Jared L. Edwards, Nicole McCuen, Prasanna G. Alluri, Betty Y.S. Kim, Wen Jiang, Jacques Lux   +12 more
wiley   +1 more source

Fostering uncertainty tolerance in anatomy education: Lessons learned from how humanities, arts and social science (HASS) educators develop learners' uncertainty tolerance

Anatomical Sciences Education, Volume 16, Issue 1, Page 128-147, January/February 2023., 2023
Abstract Uncertainty tolerance, individuals' perceptions/responses to uncertain stimuli, is increasingly recognized as critical to effective healthcare practice. While the Covid‐19 pandemic generated collective uncertainty, healthcare‐related uncertainty is omnipresent.
Michelle D. Lazarus, Amany Gouda‐Vossos, Angela Ziebell, Gabrielle Brand   +3 more
wiley   +1 more source