Results 61 to 70 of about 16,433,443 (289)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Education in the era of competences [PDF]

open access: yesRevista Electrónica Interuniversitaria de Formación del Profesorado, 2010
The paper analyses the situation of education in Europe: after fifteen years of educational policies that put education at the service of markets, the educational concept of "competence approach" is being implemented in most European countries.
Education in the era of competences
doaj  

Use of Electronic UV Dosimeters in Measuring Personal UV Exposures and Public Health Education [PDF]

open access: gold, 2020
Martin Allen   +4 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Reviewers 2021

open access: yesQualitative Research in Education, 2022
Qualitative Research in Education
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Validity and reliability of the 20-m run, horizontal leap, and four-bound tests measuring high-level mobility in neurologically impaired patients

open access: yesHong Kong Physiotherapy Journal, 2015
Background: High-level mobility (HLM) training including running forms an integral part of physical rehabilitation for neurologically impaired patients.
Marek Gorski, Master of Education (Physical Education)   +2 more
doaj   +1 more source

Advancing healthcare technology education and innovation in academia [PDF]

open access: bronze, 2020
Stephen W. Linderman   +4 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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