Results 131 to 140 of about 413,702 (268)

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

An Intervention to Support Higher Education Teachers' Teaching Processes and Well-Being: Protocol for an Intervention Study. [PDF]

JMIR Res Protoc
Postareff L, Parpala A, Nokelainen P, Kosenkranius M, Puhakka I, Pylväs L, Rintala H, Räisänen M, Wallin A.   +8 more
europepmc   +1 more source

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

Teaching of biochemistry and education of biochemists [PDF]

FEBS Letters, 1972
openaire   +2 more sources

Education Research: Teaching Neurologic Emergencies Through Serious Games: A Randomized Comparative Intervention Study. [PDF]

Neurol Educ
Heidrich M, Gudorf HF, Rauchstaedt K, Breuer-Kaiser A, Gold R, Tönges L, Biesalski AS.   +6 more
europepmc   +1 more source

CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors

Advanced Science, EarlyView.
Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen, Xiaoyun Luo, Huixin Gao, Yujing Ke, Yu Zhan, Xiaoting Xu, Xiaoxiao Xiong, Fengjiao Wei, Si Yang, Zhonghua Liu, Bolan Yu, Zhaofeng Huang, Yingjie Bian   +12 more
wiley   +1 more source

Desire, Education and Teaching

Exploring the implications of a novel theory of educational desire on the prevailing modes of educational research and theory, this book contextualises the realm of education studies through the challenging philosophies and theories of Lacan, thereby providing a genuinely alternative approach to the study of education. Structured into three main parts,
openaire   +2 more sources

Studying the Effectiveness of Video-Assisted Education in Teaching Ugandan Mothers to Monitor Their Hospitalised Infant. [PDF]

Acta Paediatr
Duby J, Kabajaasi O, Khan F, Wiens MO, Kenya Mugisha N, Nambuya H.   +5 more
europepmc   +1 more source

Field‐Frustrated Cooperative Distortions: Suppressing Jahn‐Teller Ordering via Microwave Annealing

Advanced Science, EarlyView.
Microwave annealing decouples local Jahn‐Teller distortions from long‐range cooperative ordering in CuFe2O4, stabilizing a metastable cubic phase that remains locally distorted yet globally symmetry‐frustrated. Synchrotron XRD, PDF, XPS, and in situ thermal cycling reveal how non‐equilibrium MW‐phonon interactions suppress cooperative orbital‐lattice ...
Daryoosh Vashaee, Kelvin Dsouza
wiley   +1 more source

A spherical fuzzy WASPAS approach to prioritize the factors enhancing the effectiveness of physical education classroom teaching. [PDF]

Sci Rep
Gao Y, Yu A.
europepmc   +1 more source