Results 101 to 110 of about 4,740,402 (287)

Graduate Quantum Mechanics Reform

, 2009
We address four main areas in which graduate quantum mechanics education can be improved: course content, textbook, teaching methods, and assessment tools.
Ambrose B. S., Basdevant J.-L., Bell J. S., Bohm D., Cohen-Tannoudji C., Feynman R. P., Gottfried K., L. D. Carr, Landau L. D., Mazur E., Peres A., Perkins K. K., Peskin M. E., Rae A. I. M., S. B. McKagan, Sakurai J. J., Schiff L. I., Schrödinger E., Wittmann M. C., Wittmann M. C.   +19 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Le curriculum en Finlande : un outil puissant au service de l’éducation

Revue Internationale d’Éducation de Sèvres, 2011
The article examines the central role of curriculum in the management and development of education in Finland. This role is connected to the holistic conception of curriculum, how curriculum is created by intensive cooperation of different stakeholders ...
Irmeli Halinen
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Understanding the Behavioral Differences Between American and German Users: A Data-Driven Study

Big Data Mining and Analytics, 2018
Given that the USA and Germany are the most populous countries in North America and Western Europe, understanding the behavioral differences between American and German users of online social networks is essential.
Chenxi Yang, Yang Chen, Qingyuan Gong, Xinlei He, Yu Xiao, Yuhuan Huang, Xiaoming Fu   +6 more
doaj   +1 more source

The curricular content of primary education in developing countries [PDF]

This paper examines the curriculum policies for primary schools in a wide range of developing countries in the 1980s and, to a lesser extent, the 1960s.
Benavot, Aaron, Kamens, David
core  

The Connection Strategy: Preparing Young People to Succeed in College and Beyond [PDF]

, 2008
Describes the P-16 approach of linking education strategies from preschool through college graduation to better prepare low-income minority students.
Jeanne Jehl
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source