Results 101 to 110 of about 14,139,318 (310)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Introduction: Transnational views and experiences on bilingual and second language teacher education
This is an Accepted Manuscript of a book chapter published by Routledge/CRC Press in Transnational approaches to bilingual and second language teacher education on 2024, available online: http://www.routledge.com/9781032391434Bilingual education aims to ...
Ramírez Verdugo, María Dolores
core +1 more source
In the last 10 years or so, the need to introduce changes to curricula has increasingly been evoked and which puts into question the pertinence of these changes as well as their coherence with the ideal of inclusive inclusion.
Renato Opertti, Leana Duncombe
doaj +1 more source
[Systematization of food and nutrition education content based on national kindergarten curriculum: a qualitative formative study]. [PDF]
Kim JH, Shim E, Baik E.
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Curricula are regularly subject to studies in comparative education, mainly on an international scale. While these studies are clearly worthwhile, the aim of this article is to demonstrate through a concrete example that comparative studies may also be ...
Sabine Soetewey +2 more
doaj +1 more source
Validation of a Questionnaire of Food Education Content on School Catering Websites in Spain. [PDF]
Rico-Sapena N +2 more
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
The article analyzes and systematizes different approaches to understanding the concept of “academic freedom”, which is identified with freedom of speech, freedom of research and freedom of teaching in an academic environment.
S. V. Zaiets
doaj
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source

