Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Demand for Higher Education Programs: The Impact of the Bologna Process [PDF]
The Bologna process aims at creating a European Higher Education Area where inter-country mobility of students and staff, as well as workers holding a degree, is facilitated. While several aspects of the process deserve wide public support, the reduction
Ana Rute Cardoso +3 more
core +3 more sources
The Entrepreneurial President: Proceedings from the Conference “The Entrepreneurial President” [PDF]
[Excerpt] Each year, the Institute for Community College Development offers a leadership program on critical issues for community colleges. In August 2005, the issue was entrepreneurship. The Entrepreneurial College was a great success, but when it ended,
Institute for Community College Development +2 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
A Research on the System of Master Education in Archival Science in Mainland China
A relatively complete system of master education in archival science in mainland China has been achieved after more than three decades of development. Through surveys on and content analysis of websites, websites of current 29 departments which recruit ...
Yan Zhang, Mei-Ling Wang
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Embedding library in study structure [PDF]
In Europe, the Bologna process aims at the harmonisation of the structure of higher education in order to facilitate mobility. In the context of engineering education, the trans-national recognition of engineering degrees, academically and professionally,
Heino, Kirsi, Palmgren, Virpi
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Application of a Program to Improve Personal Development in Future Physical Education Teachers of the Degree in Education and Its Relationship with Wisdom [PDF]
Milagros Arteaga Checa +2 more
openalex +1 more source
TEACHER PERFORMANCE OF WOOD CONSTRUCTION DEPARTMENTIN STUDY PROCESS IN THE IMPLEMENTATION OF PIONEERING OF SCHOOL WITH INTERNATIONAL STANDARD (RSBI) AT SMK N 2 PENGASIH [PDF]
Today, pioneering of school with international standard (RSBI) becomes a program considered by the government. Based on SK DPSMK 4294/C5.3/Kep/KU/2009, SMKN 2 Pengasih has been trusted by the government to implement this program.
Singgih Kurniadi, Isnanto
core

