Results 81 to 90 of about 455,239 (314)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Systematic Identification of Candidate Genes for Inherited Retinal Disease Gene Therapy Integrating Worldwide IRD Cohort and Single-Cell Analysis

Journal of Ophthalmology
Trial Registration: ClinicalTrials.gov identifier: NCT01482195, NCT03316560, NCT06333249, NCT06275620, NCT04850118 ...
Ching-Yun Wang, Lawrence Chen, Ting-Yi Lin, Shun-Ping Huang   +3 more
doaj   +1 more source

Narratives of Students and Alumni from a Degree Program in Portuguese as an Additional Language: Signs of the Potential for Building an Other Internationalization [PDF]

Revista Brasileira de Linguística Aplicada
: The objective of this article is to present a research project and analyze how students, who are studying to become teachers of Portuguese as a Second Language/Additional Language (PSL/PAL) in a degree program at a public university in Brazil, narrate ...
Ana Cecília Cossi Bizon, Louise Hélène Pavan   +1 more
doaj   +1 more source

A unique degree program for pre-pharmacy education: An undergraduate degree in pharmaceutical sciences

Currents in Pharmacy Teaching and Learning, 2018
Within the coming decade, the demand for well-trained pharmacists is expected to only increase, especially with the aging of the United States (US) population.To help fill this growing demand, the University of California, Irvine (UCI) aims to offer a unique pre-pharmacy degree program and has developed a Bachelor of Science (BS) degree in ...
openaire   +4 more sources

Middle Childhood Education Master\u27s Degree Annual Program Outcomes Assessments, 2022-23

, 2023
This report reviews Wright State University\u27s Middle Childhood Education Master\u27s Degree program for the 2022-2023 academic ...
College of Health, Education, and Human Services, Wright State University
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

EDUCATION QUALITY'S MONITORING IN THE CONTENT OF MASTER'S STUDENTS' TRAINING: EXPERIENCE OF DESIGNING

Вестник Северо-Кавказского федерального университета, 2022
This paper deals with reasons for urgency of master's students' training for monitoring activities in education. The article presents experience of designing the structure and content of the academic discipline «Education Quality's Monitoring» within the
Marianna Arutyunyan
doaj  

Expanding the Scope of Faculty Educator Development for Health Care Professionals

Journal of Educators Online, 2009
Although many medical institutions offer faculty development in education, this does not provide the in-depth knowledge of the science of teaching required for medical education research and careers in medical education.
Kadriye O. Lewis, Ed.D., Raymond C. Baker, M.D., M.Ed.   +1 more
doaj   +1 more source

Middle Childhood Education Baccalaureate Degree Annual Program Outcomes Assessments, 2021-22

, 2022
This report reviews Wright State University\u27s Middle Childhood Education Baccalaureate Degree program for the 2021-2022 academic ...
College of Health, Education, and Human Services, Wright State University
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source