Results 71 to 80 of about 2,650,294 (311)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A Research on the System of Master Education in Archival Science in Mainland China
Tūzī yǔ dàng’àn xuékān, 2016 A relatively complete system of master education in archival science in mainland China has been achieved after more than three decades of development. Through surveys on and content analysis of websites, websites of current 29 departments which recruit ...
Yan Zhang, Mei-Ling Wang
doaj +1 more source
The Entrepreneurial President: Proceedings from the Conference “The Entrepreneurial President” [PDF]
, 2006 [Excerpt] Each year, the Institute for Community College Development offers a leadership program on critical issues for community colleges. In August 2005, the issue was entrepreneurship. The Entrepreneurial College was a great success, but when it ended,
Institute for Community College Development +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Partnering with Districts in Principal Preparation: Key Program Features in Strengthening Aspiring Principals’ Understanding of Issues of Equity and Excellence [PDF]
, 2018 The need for increased numbers of students of all ethnic groups to access and succeed in postsecondary education is a 21st century reality (Swail, Cabrera, & Lee, 2004). As Swail, Cabreraet al.
Alford, Betty, Hendricks, Stacy
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
TEACHER PERFORMANCE OF WOOD CONSTRUCTION DEPARTMENTIN STUDY PROCESS IN THE IMPLEMENTATION OF PIONEERING OF SCHOOL WITH INTERNATIONAL STANDARD (RSBI) AT SMK N 2 PENGASIH [PDF]
, 2011 Today, pioneering of school with international standard (RSBI) becomes a program considered by the government. Based on SK DPSMK 4294/C5.3/Kep/KU/2009, SMKN 2 Pengasih has been trusted by the government to implement this program.
Singgih Kurniadi, Isnanto
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Journal of OphthalmologyTrial Registration: ClinicalTrials.gov identifier: NCT01482195, NCT03316560, NCT06333249, NCT06275620, NCT04850118 ...
Ching-Yun Wang +3 more
doaj +1 more source