Results 111 to 120 of about 12,985,568 (359)
Education Policy and Intergenerational Educational Persistence: Evidence from rural Benin [PDF]
arXivThis paper employs a nonlinear difference-in-differences approach to empirically examine the Maximally Maintained Inequality (MMI) hypothesis in rural Benin. The findings of this study confirm the MMI hypothesis. In particular, it is observed that when 76% of educated parents choose to educate their daughters in the absence of educational programs, in ...
arxiv
Where do UK clinicians find information at the point of care? A pragmatic, exploratory study
BMC Primary CareAim To describe where clinical information is contemporarily and commonly found in UK primary care, what is favoured by clinicians, and whether this is (1) publicly funded (2) has commercial potential conflicts of interest.
Margaret McCartney +8 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Revitalizing Sex Education for Chinese Children: A Formative Study [PDF]
arXivSex education helps children obtain knowledge and awareness of sexuality, and protects them against sexually transmitted diseases, pregnancy, and sexual abuse. Sex education is not well taught to children in China -- both school-based education and parental communication on this topic are limited. To interrogate the status quo of sex education in China
arxiv
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
How Gender and Birth Order Affect Educational attainment Inequality within-Families: Evidence from Benin [PDF]
arXivThis paper examines how gender, birth order, and innate ability shape within-household disparities in children's educational attainment in developing countries. Using data from Benin, I find that in households with non-educated parents, gender and birth order drive over two-thirds of the average educational attainment disparities among adult children ...
arxiv