Results 121 to 130 of about 645,451 (263)

Current state of geriatric services in Georgia: education, policy gaps, and recommendations. [PDF]

Front Public Health
Macharadze T.
europepmc   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Gifted but Misunderstood? An Interpretive Systematic Review of Gifted Education Policy, Practice, and Socio-Emotional Experience in England. [PDF]

J Intell
Karakaş Mısır S, Thomas M.
europepmc   +1 more source

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

Dual Aspects of COVID-19 on Facilitating Conditions and Students’ Willingness to Continue Online Learning

Educational Process: International Journal
Background/purpose. The crisis caused by the COVID-19 pandemic has altered the direction of education worldwide, emphasizing the prospects and problems of using online learning platforms.
Md.Abu Issa Gazi, Muhammad Khalilur Rahman, Mohammad Bin Amin, Md Arafat Hossain, Moniya Sultana, Abdul Rahman bin S Senathirajah, Veronika Fenyves   +6 more
doaj   +1 more source

Understanding education policy preferences: Survey experiments with policymakers in 35 developing countries. [PDF]

World Dev
Crawfurd L, Hares S, Minardi A, Sandefur J.   +3 more
europepmc   +1 more source

UNICEF's lessons learned from the education response to the COVID-19 crisis and reflections on the implications for education policy. [PDF]

Int J Educ Dev, 2021
Lennox J, Reuge N, Benavides F.
europepmc   +1 more source

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

Advanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu, Guangzhao Pan, Lele Zhang, Xiangliu Chen, Kui Zhang, Yang Lu, Zibo Duan, Aiping Chen, Hailong Shen, Yuxi Zhang, Xiaowu Dong, Jinzhou Huang, Xing Huang, Kai Miao, Qian Hua, Fangfang Tao, Weidong Zhang, Jiang‐Jiang Qin   +17 more
wiley   +1 more source

Cluster-Informed Policy Design for School Administrators in Vietnam: A Data-Driven Perspective on Digital Readiness

Educational Process: International Journal
Background/purpose. Digital transformation in education is a key factor in improving the quality of teaching and school management. However, readiness for digital transformation is not solely a matter for teachers—it is also a critical concern for ...
Nguyen Thi Minh Nguyet , Vu Thi Mai Huong , Bui Quang Vinh , Pham Ngoc Long   +3 more
doaj   +1 more source

Restoring a sense of safety among survivors of sexual harassment in higher education: policy recommendations from the UNI4EQUITY multinational study. [PDF]

Front Sociol
Jaskulska S, Jankowiak B, Perez-Martrnez V, Porru S, Carta A, Wallner M, Stifter V, Topa J, Andruszkiewicz I, Waszyńska K, Munoz-Haba A, Carrasco JM, Vives-Cases C.   +12 more
europepmc   +1 more source