Results 91 to 100 of about 8,294,811 (306)

Integrating procurement, prescription, and resistance data to strengthen antimicrobial stewardship: insights from a public health institution in India

open access: yesFrontiers in Microbiology
IntroductionSustained and sub-optimal antimicrobial use drives antimicrobial resistance (AMR), a major health systems challenge in low- and middle-income countries (LMICs) such as India.
Vinay Modgil   +11 more
doaj   +1 more source

Le chardon et la rose

open access: yesRevue Internationale d’Éducation de Sèvres, 2016
This article provides an overview of the historical reasons and political and constitutional contexts that have led England and Scotland to adopt very different approaches to common education.
Alan Britton
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The Utility And Recommendations Of Adapted Physical Activity In The Care Of People With Autism Spectrum Disorder In A Sports Environment

open access: yesمجلة العلوم و التكنولوجية للنشاطات البدنية و الرياضية
This research aims to evaluate the impact of an adapted sports programme on children with autism spectrum disorder (ASD), through an experimental design based on a comparison between an experimental group that received the programme and a control group ...
ZENATI yassine   +2 more
doaj   +1 more source

Ce qu’il y a de commun, de différent et d’inégal dans le curriculum de l’éducation de base en Espagne

open access: yesRevue Internationale d’Éducation de Sèvres, 2016
Basic education is the cornerstone of an educational system with the curriculum at its core, as it reflects the meaning that a community intends to give to the universal schooling project.
Juan Carlos González Faraco   +1 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Éducation gratuite et obligatoire : une étude sur le cas du Libéria

open access: yesRevue Internationale d’Éducation de Sèvres, 2016
This article examines what Liberian schools are teaching to students under the free, compulsory basic education policy. The authors conducted qualitative research among sixty stakeholders in education.
Charles Gbollie   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The roles of non-state providers in ten complementary education programmes

open access: yes, 2010
This contribution reviews ten case studies of complementary education programmes conducted by the USAID-funded Educational Quality Improvement Program 2. The state-non-state relationship in each case is explored to reveal the arrangements that permit non-
Joseph DeStefano   +3 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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