COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Promising practices for the design and implementation of sexuality education programmes for youth in India: a scoping review. [PDF]
Sex Reprod Health Matters, 2023 Pattathil N, Roy A.
europepmc +1 more source
Regulations for removing the duty on maintained schools to follow the information and communication technology (ICT) National Curriculum programmes of study, attainment targets and statutory assessment arrangements [PDF]
, 2012 "The Government has confirmed that it plans to remove the duty on maintained schools to follow the existing ICT Programmes of Study, associated Attainment Targets and statutory assessment arrangements under section 91 of the Education Act 2002.
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Rates of qualification from postgraduate research degrees : projected study outcomes of full-time students starting postgraduate research degrees in 2008-09 and 2009-10 [PDF]
, 2012 "This report introduces a new approach to measuring rates of qualification from research degree study. It provides qualification rates of students on postgraduate research degree programmes at higher education institutions in England" - front ...
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Scaffolding in Health Sciences Education Programmes: An Integrative Review. [PDF]
Med Sci Educ, 2023 Masava B, Nyoni CN, Botma Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Unravelling the impact of dental workforce training and education programmes on policy evolution: a mixed-method study protocol. [PDF]
Health Res Policy Syst, 2023 Lin GSS, Goh SM, Halil MHM.
europepmc +1 more source
Participation of Foreign Graduate Students in Campus-Based Non-Formal Education Programmes in Universiti Putra Malaysia [PDF]
, 2008 This study examined participation in campus based non-formal education programmes among foreign graduate students in Universiti Putra Malaysia and its correlates.
Amadhila, Helena Naitsuwe
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