Results 101 to 110 of about 8,294,811 (306)
The role of youth programmes in the transition from school to work [PDF]
The purpose of the study is to investigate how labour market regulation, modified by educational systems, affects the magnitude, composition and targeting of Youth Programmes.
Schröder, Lena
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Parenting programmes in South Africa: investigating design and evaluation practices [PDF]
, 2012 Includes abstract.Includes bibliographical references.Parenting programmes have been shown to have wide-ranging benefits, including the prevention of behavioural and emotional problems in children as well as child maltreatment.
Wessels, Inge
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
European Union programmes for education and vocational training: development and impact [PDF]
, 2003 This paper investigates the development and impact of European Union (EU) programmes in education and training. The programmes must be regarded in the wider context of gradual assumption of competencies in the field of education and training by the ...
Ertl, Hubert
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
The impact of sports programmes on youth crime [PDF]
, 2004 This thesis examines how and why sports programmes working with young people might contribute to crime reduction. The research focused on three case study programmes, selected with reference to a mechanism of crime reduction through pro-social ...
Nichols, Geoff
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
What is the impact of education programmes on children’s learning and school participation? [PDF]
, 2016 Most education programmes typically improve either school enrolment and attendance or learning outcomes. They rarely improve both. What works in most contexts Cash transfers had the largest and most consistent positive effects on increasing school ...
3ie. International Initiative for Impact Education
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