Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Revue Internationale d’Éducation de Sèvres, 2015 History is a long-established discipline in schools in France. Since its creation it has been placed under the aegis of politics, making it subject to frequent polemics about what should be taught, and how.
Patricia Legris
doaj +1 more source
Assessment in vocational programmes in the further education sector in England: report from the Inspectorate (National survey report, January 1995) [PDF]
, 1995 This national survey report is concerned with the assessment of students attending all types of vocational education and training programmes offered by further education sector colleges in England.
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Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Analysis of international graduate programmes structures for engineering education [PDF]
, 2010 This article traces the evolution of graduate study in Engineering in Ireland over three decades. Very few studies have shown the different norms and structures of graduate programmes in Ireland.
Brabazon, Dermot +3 more
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YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Promoting widening participation and higher education: Lessons from a four year intervention programme [PDF]
, 2008 Since the labour government came to power in 1997, a major policy has been to increase the participation rates of those entering higher education, particularly those from lower-socio economic backgrounds. Just over 10 years later, little has changed. The
Pinheiro-Torres, C, Portman-Smith, C
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A comparison of the effectiveness of three parenting programmes in improving parenting skills, parent mental-well being and children's behaviour when implemented on a large scale in community settings in 18 English local authorities : the parenting early intervention pathfinder (PEIP) [PDF]
, 2011 Background There is growing evidence that parenting programmes can improve parenting skills and thereby the behaviour of children exhibiting or at risk of developing antisocial behaviour.
Davis, Hilton +2 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Le curriculum en Finlande : un outil puissant au service de l’éducation
Revue Internationale d’Éducation de Sèvres, 2011 The article examines the central role of curriculum in the management and development of education in Finland. This role is connected to the holistic conception of curriculum, how curriculum is created by intensive cooperation of different stakeholders ...
Irmeli Halinen
doaj +1 more source