Results 21 to 30 of about 86,701 (262)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Assessing professional behaviors: a self-administered scale for medical students during clerkships

BMC Medical Education
Background Medical professionalism is a core competency for medical students during clerkships for further professional development. Given that the behavior-based framework could provide clear insight and is easy to assess, the study aimed to create a ...
Chunyu Xin, Xinzhi Song, Simeng Wang, Xuemei Cui, Ning Ding, Deliang Wen   +5 more
doaj   +1 more source

Quantile Regression of Cognitive Ability and Achievement Inequality Before and After the Pandemic in One State

Journal of Intelligence
This study draws from two cohorts of students (total N = 10,508) to examine cognitive ability and achievement inequality around the COVID-19 pandemic. Before and after the pandemic, two groups of Arkansas students were given both the Cognitive Abilities ...
Al Mansor Helal, Jonathan Wai
doaj   +1 more source

Superlubricity and Corrosion Inhibition Properties of Solvate Ionic Liquids in Hybrid Carbon Fiber Reinforced Plastic–Steel Interfaces

Advanced Engineering Materials, EarlyView.
Solvate ionic liquids lubrication reduced the coefficient of friction by ∼60% compared to dry sliding, reaching steady‐state values as low as 0.04–0.05. Corrosion weight‐loss measurements in 1 M HCl further demonstrated significant inhibition behavior, with only 100 ppm of [Li(G3)][TFSI] (∼68.5 μL/L) reducing corrosion‐product weight loss by 63 ...
Sameh Dabees, Timothy Harte, Bhagya Dharmasiri, Y. Athulya Wickramasingha, David J. Hayne, Daniel J. Eyckens, Luke C. Henderson   +6 more
wiley   +1 more source

Perceptions, attitudes and behaviors regarding professionalism and their relationships reported by newly enrolled Chinese residents

BMC Medical Ethics
Background The professionalism perceptions of newly enrolled residents determine how to implement targeted professionalism training during residency, but few studies have paid attention to this point.
Xinzhi Song, Chunyu Xin, Honghe Li, Ning Ding, Yan Wang, Charice Augustine, Deliang Wen   +6 more
doaj   +1 more source

Polarizable Vanadium Dipoles Promote Water Dissociation on Vanadium‐Based Metal Organic Framework

Advanced Functional Materials, EarlyView.
The polarization of unpaired V 3d electrons weakens the H─O bond to improve water dissociation by the dual Vδ+:O─H and Pλ−:H─O coupling hydrogen bonds formation and relaxation. P@V‐MOF electrocatalyst shows low overpotentials (94 mV in acid, 178 mV in neutral, and 77 mV in alkaline solutions) with excellent stability for effective overall water ...
Xinjuan Liu, Jun Xu, Minmin Fan, Jingcheng Xu, Mengyuan Li, Yun Gong, Weiwei Yang, Lei Li, Yong Zhou, Deqiang Zhao, Yuhua Xue, Xingtao Xu, Chang Q. Sun, Liming Dai   +13 more
wiley   +1 more source

The cultural adaption and validation of the Self-Regulated Learning Perception Scale (SRLPS) and the development of its short version in Chinese medical students

BMC Medical Education
Background Self-regulated learning (SRL) is a pivotal skill in the digital era, closely correlating to academic performance and professional development, particularly within medicine, where rapid advancements in knowledge and technology demand continuous
Chunyu Xin, Xuemei Cui, Yuxin Song, Ruixue Zhang, Ning Ding, Deliang Wen   +5 more
doaj   +1 more source

Semiconducting Polymers Post‐Functionalized With Ureido‐Pyrimidinone for Robust Stretchable Transistors

Advanced Functional Materials, EarlyView.
The design of intrinsically robust stretchable semiconducting polymers was achieved through OTBS‐mediated post‐functionalization of PDPP2T side chains with UPy units, generating dual hydrogen‐bonding motifs comprising weaker urethane linkages and strong quadruple UPy interactions along the long alkyl side chain, which is crucial for achieving desirable
Dinda Bazliah, Livy Laysandra, Kosuke Terayama, Xingyu Yang, Atsushi Isobe, Tai‐Chin Chiang, Tsuyoshi Michinobu, Yu‐Cheng Chiu   +7 more
wiley   +1 more source

The challenge of educational reform

Current Musicology, 2019
Current Musicology, No 4 (1966): Current ...
openaire   +3 more sources

EDUCATIONAL REFORM IN TURKEY [PDF]

The Muslim World, 1917
n ...
openaire   +2 more sources