Results 61 to 70 of about 2,553,417 (291)

Do university students, alumni, educators and employers link assessment and graduate employability? [PDF]

, 2017
Within higher education literature, assessment and graduate employability are linked and co-presented, in that quality student assessment is purported to enhance employability. This research was designed to query the extent to which these same conceptual
Crane, Linda, Kinash, Shelley, McGillivray, Laura   +2 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Evaluating large language models as raters in large-scale writing assessments: A psychometric framework for reliability and validity

Computers and Education: Artificial Intelligence
In large-scale international writing assessments, human raters often exhibit inconsistency, undermining reliability and validity. Large language models (LLMs) offer a potential solution, but their assessment reliability remains underexplored.
Yuehan Wang, Jinyan Huang, Lun Du, Yuxin Guo, Ying Liu, Rong Wang   +5 more
doaj   +1 more source

促進中文閱讀理解教學成效量化研究統合：調節變項影響與評估 Synthesis of Quantitative Research on Chinese Reading Comprehension Instruction: Analysis of Moderating Effects

Journal of Research in Education Sciences, 2019
以實徵研究證據為基礎，探討促進學生中文閱讀理解教學議題逐漸受到重視，而使用量化統合技術推動本議題的研究，亦愈趨興盛，然而，受限研究數量，鮮少文獻針對調節變項進行深入分析，據此，本研究目的除了分析促進中文閱讀理解教學之量化統合效果外，更聚 焦於探討教學介入、參與者背景特徵、個別研究品質評估等因素，對於教學效果量可能產生的調節影響。本研究經統合分析與刪除極端值，發現國內促進中文閱讀理解教學平均效果量，分別具有+0.43 立即效果（168 筆）與+0.39 延宕效果（46 筆），為近中等程度教學成效 ...
謝進昌 Jin-Chang Hsieh
doaj   +1 more source

Public perceptions of unreliability in examination results in England: a new perspective [PDF]

, 2010
Presented at the 36th International Association for Educational Assessment (IAEA) Annual Conference in Bangkok, Thailand, 22-27 August 2010. This report is about a quantitative study on public perceptions of unreliability in examination results, using an
Boyle, Andrew, He, Qingping, Opposs, Dennis   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

108 課綱第四學習階段國語文閱讀素養 Development and Validation of an Online

Journal of Research in Education Sciences, 2018
儘管聽、說、讀、寫都是108 學年度預定實施之國語文新課綱的重要元素，然由基本理念可窺知，閱讀能力是新課綱非常重要的關鍵。為發展符合新課綱第四學習階段閱讀素養所需線上評量，本研究目的為建立新課綱第四學習階段國語文素養導向評量發展模式並檢視其成效，從評量架構的建立、文本的挑選或撰寫原則、命題原則等三個方面探討，並分析素養導向試題心理計量特性以支持素養導向評量發展模式的有效性。援用三角檢證法，經由三場評量架構專家會議、20場命題工作坊，本研究取得三向度評量架構與16 項評量指標，建構五項文本的挑選或撰寫原則，
謝佩蓉 Pei-Jung Hsieh
doaj   +1 more source

Open Educational Resources (OER) Project, Fall 2016 Final Dissemination Assessment Report [PDF]

, 2017
ASSESSMENTS TARGETED FOUR CENTRAL AREAS: 1. Textbook Cost Savings 2. Student Perceptions of the OER Materials 3. Student Learning Outcomes 4.
Day, Melissa, Overson, Catherine
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source