Results 121 to 130 of about 1,332,783 (360)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

ACHIEVING GENDER EQUALITY AND WOMEN LEADERSHIP IN A SELECTED STATE UNIVERSITY IN ZIMBABWE: A FEMINIST CAPABILITIES APPROACH

open access: yesAfrican And Global Issues Quarterly
Despite international efforts towards gender equality, universities in developing countries including Zimbabwe continue to grapple with underrepresentation of women in leadership positions.
Annah Moyo, Wonder Muchabaiwa
doaj   +1 more source

Relationships Between Higher Education Leaders and Subordinates in Pakistan: A Path-Goal Approach [PDF]

open access: yes, 2008
This article is based on a quantitative research to examine the leadership behaviour of degree college principals, selected personal and organizational characteristics, acceptance of leadership, faculty job satisfaction and job expectancies.
Awan, R., Bigger, Stephen, Zaidi, N.R.
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Effects of the “High Impact Leadership for School Renewal” Project on Principal Leadership, School Leadership, and Student Achievement

open access: yesEducation Sciences
In this study, we designed an educational experiment to evaluate the High Impact Leadership for School Renewal project’s impact on principal leadership, school leadership, and student achievement.
Xin Ma   +6 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Cultivating Contextual Attributes in the Integration of Latin@ Educational Leadership [PDF]

open access: yes, 2018
Although the Latino population is growing rapidly in the United States, there is a disproportionate paucity of literature on the perspectives and challenges of Latino/a educational leaders.
Castillo, Yuleinys A, Maniss, Suzanne
core   +1 more source

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