Results 131 to 140 of about 1,332,783 (360)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Approaches to teacher development in Thailand’s basic education based on the valuable life concept

open access: yesCogent Education
In today’s educational landscape, many Thai teachers face burnout. Teacher development must therefore move beyond technical training to embrace the “valuable life” concept, emphasizing positive attitudes, meaningful experiences, and societal ...
Kanchit Pimjai   +2 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Re-conceptualising learning-centred (instructional) leadership: an obsolete concept in need of renovation [PDF]

open access: yes, 2016
For more than thirty years, ‘instructional leadership’ has been at the forefront of research and practice in school effectiveness and improvement. Governments, employers, universities and professional developers, all see it as a mainstay of raising ...
Dimmock, Clive, Tan, Cheng Yong
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Holistic, Ethical Leadership for the 21st Century [PDF]

open access: yes, 2018
The New Oxford American Dictionary (2001) delineates two definitions for a leader: “1) The person who leads or commands a group, organization, or country; a person followed by others.
Barrett, David C.
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Rapid AI-Assisted Instructional Design: Using Agentic LLM Tools to Develop UDL-Aligned Curricula for Student Veterans and Multilingual Learners

open access: yesApplied Sciences
Background/Context: Creating instructional materials that authentically meet the needs of marginalized learner groups such as student veterans, multilingual adult learners, and first-generation doctoral students demands consistent application of ...
John C. Chick, Laura T. Morello
doaj   +1 more source

Home - About - Disclaimer - Privacy