Results 81 to 90 of about 3,948,715 (264)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Frontiers in EducationThis systematic review examines how K-12 online learning has evolved in the post-COVID era, using the Science of Learning and Development (SoLD) framework to analyze whole-child development across five guiding principles. We searched ERIC, Google Scholar,
Jayson W. Richardson +2 more
doaj +1 more source
Strategies to address learner aggression in rural South African secondary schools
Koers : Bulletin for Christian Scholarship, 2013 Managing learner aggression in the school system is central to learners’ academic performance and holistic development. In order to manage learner aggression, it is important to understand the contributory factors and the forms of learner aggression ...
Gunam D. Singh, Gertruida M. Steyn
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Educational Leadership Program Newsletter May/June 2012 [PDF]
, 2012 Inside this issue: Letter from the Department Chair Alumni Spotlight: Marco Alberti An Interview with Ken Nye Educational Leadership Symposium Fall 2012 Schedule Notes of Interest Faculty & Staff Program Directoryhttps://digitalcommons.usm.maine.edu ...
Educational Leadership Program, University of Southern Maine
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Gender Issues in K-12 Educational Leadership [PDF]
, 2017 This paper serves as a review of the research literature on gender issues in K-12 educational leadership, with a primary focus on the principal and superintendency positions in the United States.
Thornton, Dr. Bill +3 more
core +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Educational Leadership Program Newsletter March 2013 [PDF]
, 2013 Inside this issue: Letter from the Department Chair The Department Welcomes Dr. Glenn Cummings State Senator Addresses Opening Meeting of the Southern Maine Partnership Thinking About Internship? Summer 2013 Registration Ongoing Faculty Position Search:
Educational Leadership Program, University of Southern Maine
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source