Results 91 to 100 of about 5,745,654 (298)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
JEM Journal of educational measurement.
, 1964 La page couverture porte en outre: JEM Journal of educational measurementComprend des ...
National Council of Measurement in Education
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Phenomenology of Sexual Dysfunctions in Chemical Warfare Victims of Sardasht City
طب جانباز, 2020 Aims: Sexual dysfunction is one of the most important factors that can play a fundamental role in the individual and social health and adjustment of people.
B. Melkari +3 more
doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Measurement Must Be Qualitative, then Quantitative, then Qualitative Again
Educational measurement is a social science that requires both qualitative and quantitative competencies. Qualitative competencies in educational measurement include developing and applying theories of learning, designing instruments, and identifying the
Ho, Andrew
core +1 more source
, 1972 THORNDIKE, Robert L. ed. Educational measurement. 2. ed., American Council on Education, Washington D. C., 1971.
Nick, Eva
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The level of motivation achievement in light of some variables among high-level students in the Sultanate of Oman [PDF]
المجلة العربية للتربية النوعيةThe study aimed to identify the level of achievement motivation in light of some variables among high level students in the sultanate of Oman, where it followed the descriptive survey approach, and the study sample consisted of (402) students of Al ...
Esam Al Lawati +2 more
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Artificial Intelligence and Educational Measurement: Opportunities and Threats
I review opportunities and threats that widely accessible Artificial Intelligence (AI)-powered services present for educational statistics and measurement.
Ho, Andrew
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