Results 61 to 70 of about 1,181,315 (316)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Research Trends and Issues in Educational Technology: a Content Analysis of Tojet (2008-2011) [PDF]
, 2012 WOS: 000308976800028This study has been conducted to evaluate the contents of articles published in the Turkish Online Journal of Educational Technology (TOJET) between 2008 and 2011.
Bozkaya, Müjgan +2 more
core
Educational epistemologies and methods in a more-than-human world
, 2017 This Special Issue asks what can be done in terrains of education and educational research beyond the fantasy of human control. This question presents a repertoire of complex issues.
Pedersen, Helena +2 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Comparing estimation methods for categorical marginal models
, 2015 Categorical marginal models are flexible models for modelling dependent or clustered categorical data which do not involve any specific assumptions about the nature of the dependencies.
Bolt, D.M. +6 more
core +1 more source
Psychometric Properties of the Academic Procrastination Scale in an Iranian Sample
SAGE OpenAcademic procrastination, the tendency to delay academic tasks without reasonable justification, has significant implications for students’ academic performance and overall well-being. To measure this construct, numerous scales have been developed, among
Mahdi Ghorbankhani, Keyvan Salehi
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source